Methods of identifying compounds that modulate IL-4...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007100, C435S016000, C435S023000, C435S024000, C435S975000, C530S300000

Reexamination Certificate

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06979549

ABSTRACT:
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a CLLD8 protein as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.

REFERENCES:
patent: 2004/0014638 (2004-01-01), Masuda et al.
Hideaki et al., Cancer Research (2001) 61:2870-2877.

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