Methods of human prostate cancer diagnosis

Details Methods of human prostate cancer diagnosis Methods of human prostate cancer diagnosis

1994-12-23

1997-08-19

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 2431, 436 64, 436813, 935 78, C12Q 168, C07H 2104

Patent

active

056587309

ABSTRACT:
Disclosed are diagnostic techniques for the detection of human prostate cancer. Genetic probes and methods useful in monitoring the progression and diagnosis of prostate cancer are described. The invention relates particularly to hybridization methods for evaluating the prevalence of gene amplification in a limited regions of human chromosome 8q24.

REFERENCES:
Denis, European Urology (1993) 24: 13-18.
Takahashi et al Cancer Research (1994) 54: 3574-3579.
Alcaraz et al., "Aneuploidy and Aneusomy of Chromosome 7 Detected by Fluorescence in Situ Hybridization Are Markers of Poor Prognosis in Prostate Cancer," Cancer Research, 54:3998-402, 1994.
Bova et al., "Homozygous Deletion and Frequent Allelic Loss of Chromosome 8p22 Loci in Human Prostate Cancer," Cancer Research, 53:3869-3873, 1993.
Brothman et al., "Frequency and Pattern of Karyotypic Abnormalities in Human Prostate Cancer," Cancer Research, 50:3795-3803, 1990.
Fukumoto et al., "Analysis of Gene Amplification in Human Tumor Cell Lines," Genetics, 85:6846-6850, 1988.
Guan et al., "Generation of Bank-Specific Painting Probes from a Single Microdissected Chromosome," Human Molecular Genetics, 2(8):1117-1121, 1993.
Guan et al., "Identification of Cryptic Sites of DNA Sequence Amplification in Human Breast Cancer by Chromosome Microdissection," Nature Genetics, 8:155-161, 1994.
Kallioniemi et al., "Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors," Science, 258:818-821, 1992.
Kallioniemi et al., "Optimizing Comparative Genomic Hybridization for Analysis of DNA Sequence Copy Number Changes in Solid Tumors," Genes, Chromosomes and Cancer, 10:231-24, 1994.
Ludecke et al., "Cloning Defined Regions of the Human Genome by Microdissection of Banded Chromosomes and Enzymatic Amplification," Nature, 338:348-350, 1989.
Macoska et al., "Fluorescence in Situ Hybridization Analysis of 8p Allelic Loss and Chromosome 8 Instability in Human Prostate Cancer," Cancer Research, 54:3824-3830, 1994.
Meltzer et al., "Rapid generation of region specific probes by chromosome microdissection and their application," Nature Genetics, 1:24-28, 1992.
Milasin and Micic, "Double Minute Chromosomes in an Invasive Adenocarcinoma of the Prostate," Cancer Genet Cytogenet, 72:157-159, 1994.
Pelicci et al., "Amplification of N-myc in Untreated Human neuroblastomas Correlates with Advanced Disease Stage," Science, 224:1121-1124, 1984.
Persons et al., "Use of Fluorescent in Situ Hybridization for Deoxyribonucleic Acid Ploidy Analysis of Prostatic Adenocarcinoma," Journal of Urology, 150:120-125, 1993.
Pinkel et al., "Cytogenetic Analysis Using Quantitative, High-Sensitivity, Fluorescence Hybridization," Proc. Natl. Acad. Sci. USA, 83:2934-2938, 1986.
Visakorpi et al., "Sensitive Detection of Chromosome Copy Number Aberrations in Prostate Cancer by Fluorescence in Situ Hybridization," American Journal of Pathology, 145(3):624-630, 1994.
Zhang et al., "Rapid Isolation and Characterization of Amplified DNA by Chromosome Microdissection: Identification of IGF1R Amplification in Malignant Melanoma," Oncogene, 8:2827-2831, 1993.
Zhang et al., "Whole Genome Amplification from a Single Cell: Implications for Genetic Analysis," Proc. Natl. Acad. Sci. USA, 89:5847-5851, 1992.

Affiliated with

Also associated with

Rating

Methods of human prostate cancer diagnosis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of human prostate cancer diagnosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of human prostate cancer diagnosis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1103806