Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2006-05-16
2006-05-16
Housel, James C. (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S004000, C435S007200, C435S007400, C435S007710, C435S007720, C435S007900
Reexamination Certificate
active
07045283
ABSTRACT:
This invention provides methods of identifying ligands that are internalized into a cell. The methods typically involve i) contacting the cell with a reporter non-covalently coupled to a ligand; ii) dissociating the reporter from the ligand and removing dissociated reporter from the surface of the cell; and iii) detecting the reporter within said cell (if any is present) where the presence of the reporter within said cell indicates that the ligand binds to an internalizing receptor and is internalized.
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Kirpotin Dimitri B.
Marks James D.
Nielson Ulrik B.
Horne Angela P.
Housel James C.
Hunter Tom
Lucas Zachariah
Quine Intellectual Property Law Group P.C.
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