Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-04-05
2005-04-05
McGarry, Sean (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C435S006120, C435S325000, C435S375000, C536S023100, C536S024500
Reexamination Certificate
active
06875749
ABSTRACT:
A method of facilitating vascular growth in a subject in need of such treatment comprises inhibiting EMAP II activity in the subject by an amount effective to stimulate vascular growth in the subject (e.g., in the lungs or heart of the subject). Pharmaceutical formulations useful for carrying out such methods (e.g., an antibody that specifically binds to EMAP II in a pharmaceutically acceptable carrier) and screening techniques useful for identifying additional compounds that can be used for carrying out such methods are also disclosed.
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Knies et al.;Regulation of Endothelial Monocyte-Activating Polypeptide II Release by Apoptosis, Proc. Natl. Acad. Sci. USA, 95:12322-12327 (1998).
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Supplementary Partial European Search Report for European Patent Application Serial No. EP99958914 dated Jan. 21, 2003.
Gebb Sarah A.
Schwarz Margaret A.
Zhang Fangrong
Children's Hospital Los Angeles
McGarry Sean
Myers Bigel & Sibley & Sajovec
National Jewish Medical and Research Center
Schultz J D
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