Methods of expressing integrin β 6 subunits

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007230, C530S388220

Reexamination Certificate

active

10894643

ABSTRACT:
The present invention provides substantially pure integrins containing a novel β subunit designated as β6. The novel β6subunit forms heterodimers with αvand αf. Methods of controlling cell adhesion using the β6-containing integrins are also provided.

REFERENCES:
patent: 5204445 (1993-04-01), Plow et al.
Breuss et al Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues. J Histochem Cytochem. Oct. 1993;41(10):1521-7.
Cheresh, et al.; “A Novel Vitronectin Receptor Integrin (αvβx) Is Responsible for Distinct Adhesive Properties of Carcinoma Cells;” Apr. 1989; pp. 56-69; 57.
Freed, et al.; “A novel intergrin β subunit is associated with the vitronectin receptor α subunit (αv) in a human osteosarcoma cell line and is a substrate for protein kinase C;”The EMBO Journal; 1989; pp. 2955-2965; 8:10.
Holzmann, et al.; “Identification of a Murine Peyer's Patch-Specific Lymphocyte Homing Receptor as an Integrin Molecule with an α Chain Homologous to Human VLA-4α;”Cell; Jan. 1989; pp. 37-46; 56.
Kajiji, et al.; “A novel integrin (αEβ4) from human epithelial cells suggests a fourth family of integrin adhesion receptors;”The EMBO Journal; 1989; pp. 673-680; 8:3.
Kramer, et al.; “Integrin Structure and Ligand Specificity in Cell-Matrix Interactions;”Molecular and Cellular Aspects of Basement Membranes, edited by David H. Rohrbach and Rupert Timpl; 1993; Chapter 12; pp. 239-265.
Ramaswamy, et al.; “Cloning, primary structure and properties of a novel human integrin β subunit;”The EMBO Journal; 1990; pp. 1561-1568; 9:5.
Ruoslahti, et al.; “New Perspectives in Cell Adhesion: RGD and Integrins;”Science; Oct. 1987; pp. 491-497; 238.
Sheppard, et al.; “Complete Amino Acid Sequence of a Novel Integrin β Subunit (β6) Identified in Epithelial Cells Using the Polymerase Chain Reaction;”The Journal of Biological Chemistry; 1990; pp. 11502-11507; 265:20.
Sheppard, et al.; “Use of Homology PCR to Identify a Novel Integrin Beta Chain from Airway Epithelium;”Am. Rev. Respir. Dis.; 141:A707; World Conference on Lung Health; Boston, MA; May 20-24, 1990.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of expressing integrin β 6 subunits does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of expressing integrin β 6 subunits, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of expressing integrin β 6 subunits will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3825162

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.