Methods of expanding stem and progenitor cells and expanded...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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C435S372000, C435S375000, C435S383000

Reexamination Certificate

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10418639

ABSTRACT:
Ex vivo and in vivo methods of expanding a population of stem and/or progenitor cells, while at the same time reversibly inhibiting differentiation of the stem and/or progenitor cells by providing the stem and/or progenitor cells with an effective amount of at least one copper chelate, so as to maintain a free copper concentration available to said cells substantially unchanged, to thereby expand the population of said stem and/or progenitor cells, while at the same time reversibly inhibit differentiation of said stem and/or progenitor cells.

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