Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Reexamination Certificate
2011-05-10
2011-05-10
Stucker, Jeffrey (Department: 1649)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
C514S012200, C514S021200, C607S088000
Reexamination Certificate
active
07939078
ABSTRACT:
Co-administration of an effective amount of autoantigen and UV light to mucosal associated lymphatic tissue (MALT) in a patient.
REFERENCES:
patent: 4838852 (1989-06-01), Edelson
patent: 5935577 (1999-08-01), Weiner
patent: 6068844 (2000-05-01), Becker
patent: 6645504 (2003-11-01), Weiner
patent: 7226470 (2007-06-01), Kemeny
patent: 7261896 (2007-08-01), Hallenbeck
patent: 2004/0009125 (2004-01-01), Hallenbeck et al.
patent: 2004/0030368 (2004-02-01), Kemeny
patent: 2004/0204747 (2004-10-01), Kemeny et al.
patent: 2006/0292182 (2006-12-01), Kemeny et al.
patent: 2008/0107663 (2008-05-01), Groux
Cooper et al. PNAS(USA), vol. 89, pp. 8497-8501, 1992.
van Kempen et al. Int. Arch. Alllergy Immunol., vol. 122, pp. 8-19, 2000.
Csoma et al. J. Photochem. Photobiol. B: Biology, 2004, vol. 75, pp. 137-144.
Takeda et al. Stroke, 2002, vol. 33, pp. 2156-2164.
Mallat, “Induction of a Regulatory T Cell Type I Response Reduces the Development of Atherosclerosis in Apolipoprotein E-Knockout Mice”, Basic Science Reports, Circulation, 2003, pp. 1232-1237, vol. 108, American Heart Association.
Barbey, “Intranasal Treatment With Ovalbumin Cut Not The Major T Cell Epitope Ovalbumin 323-339 Generates Interleukin-10 Secreting T Cells And Results In The Induction of Allergen Systemic Tolerance”, Clinical & Experimental Allergy, 2004, pp. 654-62, vol. 34, Issue 4, Blackwell Publishing Ltd.
Ghoreishi, “Tolerance Induction by Transcutaneous Immunization through Ultraviolet-Irradiated Skin Is Transferable through CD4+CD25+ T Regulatory Cells and Is Dependent on Host-Derived IL-10”, The Journal of Immunology, 2006, pp. 2635-2644, vol. 176. The American Association of Immunologists.
Schwarz, “Mechanisms of UV-induced Immunosuppression”, Keio Journal of Medicine, 2005, pp. 165-171, vol. 54 (4), Dept. of Dermatology, University Kiel, Germany.
Ullrich, “Mechanisms Underlying UV-induced Immune Suppression”, Mutation Research 571, 2005, pp. 185-205, Elservier B.V.
Beissert, “Regulatory T Cells”, Journal of Investigative Dermatology, 2006, pp. 15-24, vol. 126, Society for Investigative Dermatology.
Weiner, “Oral Tolerance: Immune Mechanisms and the generation of Th3-type TGF-beta-secreting Regulatory Cells”, Microbes and Infection, 2001, pp. 947-954, Elsevier.
Chen, “Regulatory T Cell Clones Induced by Oral Tolerance: Suppressiono f Autoimmune Encephalomyelitis”, Science, Aug. 1994, pp. 1237-1240, vol. 265 (abstract only).
Hernandez-Pando, “The role of TNF-a in T-cell-mediated Inflammation Depends on the Th1/Th2 Cytokine Balance”, Immunology, Aug. 1994, pp. 591-595, vol. 82(4), Dept. of Medical Microbiology, UCL Med School, London, UK.
Nagler, “Oral Tolerization Ameliorates Liver Disorders Associated With Chronic Graft Versus Host Disease in Mice”, Hepatology, Mar. 2000, pp. 641-648, vol. 31(3), American Association for the Study of Liver Diseases.
Slavin, “Mucosal Administration of IL-10 Enhances Oral Tolerance in Autoimmune Encephalomyelitis and Diabetes”, International Immunology, pp. 825-833, vol. 13(6), Japanese Society for Immunology. 2001 .
Inobe, “IL-4 is a Differentiation Factor for Transforming Growth Factor-B secreting Th3 Cells and Oral Administration of IL-4 Enhances Oral Tolerance in Experimental Allergic Encephalomyelitis”, Eur. J. Immunol. 1998, pp. 2780-2790, vol. 28, Wiley-VCH Verlag GmbH, Weinheim.
Magee, Suppression Of The Elicitation Of The Immune Response to Alloantigen by Ultraviolet Radiation, Transplantation, Jun. 1989, pp. 1008-1013, vol. 47, The Williams & Wilkins Co.
Ullrich, “Does Exposure to UV Radiation Induce a Shift to a Th-2-like Immune Reaction?”, Photochemistry and Photobiology, 1996, pp. 254-258, vol. 64(2), American Society for Photobiology.
Ullrich, Specific Suppression Of Allograft Rejection After Treatment Of Recipient Mice With Ultraviolet Radiation And Allogeneic Spleen Cells:, Transplantation, Jul. 1998, pp. 115-119, vol. 46 No. 1, The Williams & Wilkins Co.
Csoma, “Intranasal Irradiation With The Xenon Chloride Ultraviolet B Laser Improves Allergic Rhinitis”, Journal of Photochemistry and Photobiology B: Biology, 2004, pp. 137-144, vol. 75, Elsevier B.V.
Liu, “Dendritic Cell Lineage, Plasticity and Cross-regulation”, Nature Immunology, Jul. 2001, pp. 585-589, vol. 2 No. 7, Nature Publishing Group.
King, “TGF-B1 Alters APC Preference, Polarizing Islet Antigen Responses toward a Th2 Phenotype”, Immunity, May 1998, pp. 601-613, vol. 8, Cell Press.
Mattsson, “Immunization with Alum—Collagen II Complex Suppresses the Development of Collagen-Induced Arthritis in Rats by Deviating the Immune Response”, Scand. J. Immunol., 1997, pp. 619-624 vol. 46, Blackwell Science Ltd.
Brewer, “Aluminium Hydroxide Adjuvant Initiates Strong Antigen-Specific Th2 Responses in the Absence of IL-4- or IL-13-Mediated Signaling1”, J. Immunology, 1999, pp. 6448-6454, vol. 163, The American Association of Radiologist.
Comoy, “In Vivo Induction Of Type 1 And 2 Immune Responses Against Protein Antigens”, International Immunology, 1997, pp. 523-531, vol. 9, No. 4, Oxford University Press.
Cribbs, “Adjuvant-dependent Modulation of Tn1 and Tn2 Responses to Immunization with B-amyloiid”, International Immunology, 2003, pp. 505-514, vol. 15, No. 4, The Japanese Society for Immunology.
Becker, “Adoptive Transfer of Myelin Basic Protein-Tolerized Splenocytes to Naive Animals Reduces Infarct Size—A Role for Lymphocytes in Ischemic Brain Injury?”, Stroke, 2003, pp. 1809-1815, American Heart Association.
Stohlman, “Activation of Regulatory Cells Suppresses Experimental Allergic Encephalomyelitis Via Secretion of IL-10”, The Journal of Immunology, 1999, pp. 6338-6344; vol. 163., The American Association of Immunologists.
Frenkel, “Nasal Vaccination with Myelin Oligodendrocyte Glycoprotein Reduces Stroke Size by Inducing IL-10-Producing CD4+ T Cells”, The Journal of Immunology, 2004, pp. 6549-6555, vol. 172, The American Association of Immunologists, Inc.
Takeda, “Induction of Mucosal Tolerance to E-Selectin Prevents Ischemic and Hemorrhagic Stroke in Spontaneously Hypertensive Genetically Stroke-Prone Rats”, Stroke, Sep. 2002, pp. 2156-64, vol. 33, American Heart Association.
Viac, “Effect of UVB 311 nm Irradiation on Normal Human Skin”, Photodermatol. Photoimmunol. Photomed., Jun. 1997, pp. 103-108, vol. 13(3), Clinique Dermatologique, Lyon France (abstract only).
Heckman,“Ultraviolet-A Radiation Induces Adhesion Molecule Expression On Human Dermal Microvascular Endothelial Cells”, Br. J. Dermatol., Sep. 1994, p. 311-318, vol. 131(3), (UVA), The Society for Investigative Dermatology (abstract only).
Schornagel, “Decreased Neutrophil Skin Infiltration After UVB Exposure in Patients with Polymorphous Light Eruption”, The Journal of Investigative Dermatology, 2004, pp. 202-206, vol. 123, The Society for Investigative Dermatology, Inc.
Strickland, TNF-a and IL-8 Are Upregulated in the Epidermis of Normal Human Skin after UVB Exposure: Correlation with Neutrophil Accumulation and E-Selectin Expression:, The Journal of Investigative Dermatology, May 1997, pp. 763-768, vol. 108(5). The Society of Investigative Dermatology, Inc.
Norris, “The Expression of Endothelial Leukocyte Adhesion Molucule-1 (ELAM-1), Intercellular Adhesion Molecule 1 (ICAM-1), and Vascular Cell Adhesion Molecule-1 (VCAM-1) in Experimental Cutaneous Inflammation: A Comparison of Ultraviolet B Erythema and Delayed Hypersensitivity”, The Journal of Investigative Dermatology, 1991, pp. 763-770, vol, 96, The Society for Investigative Dermatology, Inc.
Rahman, “E-selectin Expression in Human Endothelial Cells by TNF-a-induced Oxidant Generation and NF-kB Activation”, American Journal of Physiology (Lung Cell. Mol. Physiol
Attawia Mohamed
DiMauro Thomas M.
Holy Chantal
Lilienfeld Sean
Codman & Shurtleff
DiMauro Thomas M.
Gucker Stephen
Stucker Jeffrey
LandOfFree
Methods of enhancing the immune response to autoantigens in... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of enhancing the immune response to autoantigens in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of enhancing the immune response to autoantigens in... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2677369