Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2007-03-13
2007-03-13
Woitach, Joseph (Department: 1633)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C424S450000, C435S320100, C435S455000, C435S458000
Reexamination Certificate
active
09839707
ABSTRACT:
The present invention provides novel and surprisingly effective methods for delivering nucleic acids to cells. These methods are based upon the discovery that the presence of endosomal membrane destabilizers (e.g., calcium) leads to a dramatic increase in the transfection efficiency of plasmids formulated as SPLP, or “stabilized plasmid-lipid particles.”
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Cullis Pieter R.
Lam Angela M. I.
Palmer Lorne R.
Kelly Robert M.
Seed IP Law Group PLLC
The University of British Columbia
Woitach Joseph
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