Chemistry: analytical and immunological testing – Cancer
Reexamination Certificate
2007-12-25
2007-12-25
Ulm, John (Department: 1649)
Chemistry: analytical and immunological testing
Cancer
Reexamination Certificate
active
10375157
ABSTRACT:
The present invention provides novel polynucleotides encoding HGPRBMY23 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY23 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly renal diseases and/or disorders, colon cancer, breast cancer, and diseases and disorders related to aberrant NFKB modulation. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
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Feder John N.
Nelson Thomas C.
Neubauer Michael G.
Ramanathan Chandra S.
Ryseck Rolf-Peter
Bristol--Myers Squibb Company
D'Amico Stephen C.
Ulm John
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