Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-08-15
1998-12-08
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 698, 435 915, 4353201, 935 77, 935 78, C12Q 168, C12P 1934, C12N 1585, C07H 2104
Patent
active
058467203
ABSTRACT:
The invention provided for a method of transcriptionally modulating the expression of a gene encoding a protein of interest associated with treatment of one or more symptoms of a cardiovascular disease. Further provided is a method of determining whether a molecule not previously known to be a modulator of protein biosynthesis is capable of directly and specifically transcriptionally modulating the expression of a gene encoding a protein of interest associated with treatment of one or more symptoms of a cardiovascular disease. Screening methods, including methods of essentially simultaneously screening molecules to determine whether the molecules are capable of directly and specifically transcriptionally modulating one or more genes encoding proteins of interest associated with treatment of one or more symptoms of a cardiovascular disease, are also provided.
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Case Casey C.
Foulkes J. Gordon
Liechtfried Franz E.
Pieler Christian
Stephenson John R.
Oncogene Science, Inc.
White John P.
Zitomer Stephanie W.
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