Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2002-08-02
2010-06-29
Kolker, Daniel E. (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
Reexamination Certificate
active
07745151
ABSTRACT:
Inhibitors of Nogo Receptor (NgR)-p75 binding are used to reduce NgR-p75 binding mediated axon growth inhibition. Mixtures of NgR and p75 are used in pharmaceutical screens to characterize agents as inhibiting binding of NgR to p75 and promoting axon regeneration.
REFERENCES:
patent: WO 03031462 (2003-04-01), None
Wang et al (2002). Nature. 420, 74-78.
Jung et al. Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor. J Biol Chem. Oct. 24, 2003;278(43):42161-9. Epub Aug. 11, 2003.
He Zhigang
Kim Jieun A.
Wang Kevin C.
Children's Medical Center Corporation
Emch Gregory S
Kolker Daniel E.
Osman Richard Aron
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