Methods of determining an increased risk of a woman carrying a d

Chemistry: analytical and immunological testing – Pregnancy or ovulation

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436 86, 436 87, 436814, 436817, 436818, 436510, 435 4, 435 71, 435 74, 435 21, G01N 3348, G01N 3300, G01N 3353, G01N 33573, C12Q 100

Patent

active

061271861

ABSTRACT:
There are provided methods for assaying biological specimens for one or more of leptin, prorenin or renin in order to provide predictive information about the likelihood of a woman carrying a Downs Syndrome affected fetus.

REFERENCES:
"Serum letpin concentrations in obese women with Down Syndrome and Prader-Willi Syndrome", Cento et al., Gynecol Endocrinol; 13 (1):36-41; Feb. 1999.
"Pseudohypoaldosteronism in a child with Down Syndrome, Long-term management of salt loss by ion exchange resin administration", Saule et al., Eur J Pediatr; 142(4):286-9; Sep. 1984.

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