Methods of detection using a cellulose binding domain fusion pro

Chemistry: analytical and immunological testing – Biospecific ligand binding assay

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436503, 436504, 436512, 436515, 436516, 436518, 436529, 436530, 435 697, G01N 3352, G01N 3358, G01N 3368

Patent

active

058562010

ABSTRACT:
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

REFERENCES:
patent: 5137819 (1992-08-01), Kilburn et al.
patent: 5202247 (1993-04-01), Kilburn et al.
patent: 5328985 (1994-07-01), Sano et al.
patent: 5340731 (1994-08-01), Kilburn et al.
Bowie et al. 1990. Science 247:1306-1310.
Greenwood et al. 1992. Protein Engineering 5:361-365.
Sambrook et al. 1989. Molecular Cloning, A Laboratory Manual, 2nd edition, old Spring Harbor press, Chapter 18.
Nilsson et al., 1985, "Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors," EMBO J. 4(4): 1075-1080.
MacKay, et al., 1986, "Structure of a Bacillus subtilis endo-.beta.-1,4-glucanase gene," Nucleic Acids Res., 14(22):9159-9170.
Mehra et al., 1986, "Efficient mapping of protein antigenic determinants," Proc. Natl. Acad. Sci. USA 83:7013-7017.
Studier et al., 1986, "Use of Bacteriophage T7 RNA Polymerase to Direct Selective High-level Expression of Cloned Genes," J. Mol. Biol. 189:113-130.
Shinnick, Thomas M., 1987, "The 65-Kilodalton Antigen of Mycobacterium tuberculosis," J. of Bacteriology 169(3):1080-1088.
Cabib Enrico, 1988, "Chitinase from Serratia marcescens," Methods in Enzymology 161:460-462.
Hemmingsen et al., 1988, "Homologous plant and bacterial proteins chaperone oligomeric protein assembly," Nature 333:330-334.
Shinnick et al., 1988, "The Mycobacterium tuberculosis 65-Kilodalton Antigen Is a Heat Shock Protein Which Corresponds to Common Antigen and to the Escherichia coli GroEL Protein", Infection and Immunity 56(2):446-451.
van Eden et al., 1988, "Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis," Nature 331:171-173.
Greenwood et al., 1989, "Fusion to an endoglucanase allows alkaline phosphatase to bind to cellulose," EBS Letters 244(1):127-131.
Jindal et al., 1989, "Primary Structure of a Human Mitochondrial Protein Homologous to the Bacterial and Plant Chaperonins and to the 65-Kilodalton Mycobacterial Antigen," Mol. and Cell. Biol. 9(5):2279-2283.
Picketts et al., 1989, "Molecular Cloning of a Chinese Hamster Mitochondrial Protein Related to the Chaperonin Family of Bacterial and Plant Proteins," J. Biol. Chem. 264:12001-12008.
Saul, et al., 1989, "Nucleotide sequence of a gene from Caldocellum saccharolyticum encoding for exocellulase and endocellulase activity," Nucleic Acids RES., 17(1):439.
Billingham et al., 1990, "A Mycobacterial 65-kD Heat Shock Protein Induces Antigen-Specific Suppression of Adjuvant Arthritis, But Is Not Itself Arthritogenic," J. Exp. Med. 171:339-344.
Elias et al., 1990, "Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein," Proc. Natl. Acad. Sci. USA 87:1576-1580.
Ellis, John, 1990, "The molecular chaperone concept," Seminars in Cell Biology 1:1-9.
Jauris et al., 1990, "Sequence Analysis of the Clostridium stercorarium celZ Gene Encoding a Thermoactive Cellulase (Avicelase I): Identification of Catalytic and Cellulose-Binding Domans," Mol. Gen. Genet. 223:258-267.
Klyosov, Anatole A., 1990, "Trends in Biochemistry and Enzymology of Cellulose Degradation," Biochemistry 29(47):10577-10585.
Shoseyov et al., 1990, "Cloning of Clostridium cellulovorans Endo-1,4-.beta.-Glucanase Genes," Biochem. Biophys. Res. Commun. 169(2):667-672.
Shoseyov et al., 1990, "Cloning of 170 dKa Clostridium cellulovorans Cellulase Subunit: An Essential Protein for the Degradation of Crystalline Cellulose," Meeting of the American Abstracts of the Annual Society for Microbiology 0-24.
Shoseyov et al. 1990, "Essential 170-kDa subunit for degrdtation of crystalline cellulose by Clostridium cellulovorans cellulase, " Proc. Natl. Acad. Sci. USA 87:2192-2195.
Shoseyov et al., 1990, "Immobilized Endo-.beta.-glucosidase Enriches Flavor of Wine and Passion Fruit Juice," JAFCU 38(6):1387-1390.
Venner et al., 1990, "Nucleotide Sequences and Novel Structural Features of Human and Chinese Hamster hsp60 (Chaperonin) Gene Families," DNA Cell Biol. 9:545-552.
Venner et al., 1990, Nucleotide sequence of rat hsp60 (chaperonin, GroEL homolog) cDNA, Nucleic Acids Res. 18(17):5309.
Din et al., 1991 "Non-Hydrolytic Disruption of Cellulose Fibres by the Binding Domain of a Bacterial Cellulase," Bio/Technology 9:1096-1099.
Elias et al. 1991, "Vaccination Against Autoimmune Mouse Diabetes With a T-cell Epitope of the Human 65-kDa Heat Shock Protein," Proc. Natl. Acad. Sci. U.S.A. 88:3088-3091.
Foong et al., 1991, "Nucleotide Sequence and Characteristics of Endoglucanase Gene engB from Clostridium cellulovorans," Journal of General Microbiology 137:1729-1736.
Hermann et al., 1991, "Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells," Eur. J. Immunol. 21:2139-2143.
Shoseyov et al., 1991, "Nucleotide Sequence of Clostridium cellulovorans Gene Homologous to Cyclic-AMP Dependent Kinase," Nucleic Acids Res. 19:1710.
van Eden, Willem, 1991, "Heat-Shock Proteins as Immunogenic Bacterial Antigens with the Potential to Induce and Regulate Autoimmune Arhritis," Immunological Reviews 121:5-28.
Hansen, et al., 1992, "ceIA from Bacillus lautus PL236 Encodes a Novel Cellulose-Binding Endo-.beta.-1,4-Glucanase," Journal of Bacteriology, vol. 174(11):3522-3531.
Poole et al., 1992, "Identification of the Cellulose Binding Domain of the Cellulosome Subunit S1 from Clostridium thermocellum YS,", FEMS Microbiology Letters 99: 181-186.
Shoseyov et al., 1992, "Primary sequence analysis of Clostridium cellulovorans cellulose binding protein A," Proc. Natl. Acad. Sci. USA 89:3483-3487.
Gerngross, et al., 1993, "Sequencing of a Clostridium thermocellum gene (cipA) encoding the cellulosomal S.sub.L -protein reveals an unusual degree of internal homology," Molecular Biology, 8(2):325-334.
Hazlewood, et al., 1993, Gene sequence and properties of Cell, a family E endoglucanase from Clostridium thermocellum, Journal of General Microbiology, 139:307-316.

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