Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2011-07-05
2011-07-05
Goddard, Laura B (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Reexamination Certificate
active
07972770
ABSTRACT:
The disclosed methods address the identification and monitoring of cancer in a subject using serum peptide profiles. Such profiles allow the detection of the differential presence of certain serum peptide markers in comparison with controls. The profiles can be determined employing mass spectrometry.
REFERENCES:
patent: 2005/0059013 (2005-03-01), Chan et al.
patent: 2007/0054329 (2007-03-01), Fung et al.
patent: 2008/0317771 (2008-12-01), Spagnoli et al.
patent: WO-2006/034032 (2006-03-01), None
patent: WO-2006/099126 (2006-09-01), None
patent: PCT/ISA/210 (2008-05-01), None
Adam et al (Cancer Research, 2002, 62:3609-3614).
Koomen et al (Rapid Communications in mass Spectrometry, 2004, 18:2537-2548).
Marshall et al (J of Proteome Research, 2003, 2:361-371).
Peccerella et al (Clinical Chemistry, 2010, 56:272-280).
Tockman et al (Cancer Res., 1992, 52:2711s-2718s).
Villanueva et al (J Cinical Investigation; 2006, 116:271-284, IDS).
WO-Form PCT/ISA/237, May 22, 2008, Written Opinion.
Song et al. Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay. Clinical Chemistry. Jun. 2006. vol. 52. p. 1045-1053.
Fung et al. Classification of cancer types by measuring variants of host response proteins using SELDI serum assays. Int J Cancer. 2005. vol. 115. p. 783-789.
Villanueva et al. Differential exoprotease activities confer tumor-specific serum peptidome patterns. J of Clinical Investigation. Jan. 2006. vol. 116, p. 271-284.
Koomen et al. Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discover. J of Proteome Research. May/Jun. 2005. vol. 4. p. 972-981.
Caputo et al. Peptide profiling in epithelial tumor plasma by the emerging proteomic techniques. J. of Chromatography. May 2005. vol. 819, p. 59-66.
Tempst Paul
Villanueva Josep
Chiang Elbert
Edwards Angell Palmer & & Dodge LLP
Goddard Laura B
Lauro, Esq. Peter C.
Memorial Sloan-Kettering Cancer Center
LandOfFree
Methods of detection of cancer using peptide profiles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of detection of cancer using peptide profiles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of detection of cancer using peptide profiles will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2716789