Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-05
1997-03-11
Walsh, Stephen G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 4, 435 74, 435 76, 435 792, 435 691, 435 696, 4351723, 435183, 435 15, C12N 910, C12N 912, C12N 1100, C12Q 148
Patent
active
056100191
ABSTRACT:
Isolated polynucleotide molecules encoding mammalian phospholipid transfer proteins (PLTP) and phospholipid transfer protein polypeptides are disclosed. The DNA molecules are transformed or transfected into host cells and the cells cultured to produce recombinant PLTP and PLTP polypeptides. PLTP and PLTP polypeptides may be combined with a pharmaceutically acceptable vehicle and administered to patients to regulate phospholipid transfer activity and thereby obtain a more favorable lipoprotein profile in the blood. The proteins and polypeptides may also be used within methods to measure phospholipid transfer activity or identify inhibitors of phospholipid transfer activity.
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Adolphson Janet L.
Albers John J.
Day Joseph R.
Lofton-Day Catherine E.
Kemmerer Elizabeth C.
Leith Debra K.
Parker Gary E.
Sawislak Deborah A.
Walsh Stephen G.
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