Chemistry: analytical and immunological testing – Peptide – protein or amino acid – Glycoproteins
Patent
1989-06-01
1992-05-05
Hill, Jr., Robert J.
Chemistry: analytical and immunological testing
Peptide, protein or amino acid
Glycoproteins
436 67, 436178, 436501, 436518, 436815, G01N 3352
Patent
active
051107457
ABSTRACT:
The invention discloses novel methods of detecting glycated proteins in test samples of blood and methods of detecting chronic hyperglycemia. The test sample is contacted with a binder composition under conditions which allow binding of glycated protein in the test sample to at least a portion of the binder composition. The test sample is then exposed to a glycated compound affixed to a solid support under conditions which allow raction of unbound binder composition from the previous step to at least a portion of the glycated compound on the solid support. The glycated compound affixed to a solid support from the previous step which did not react with the unbound binder composition is then reacted with a detecting agent and the detecting agent is detected.
REFERENCES:
patent: 4200435 (1980-04-01), Stroupe
patent: 4247533 (1981-01-01), Cerami et al.
patent: 4255385 (1981-03-01), Stroupe
patent: 4269605 (1981-05-01), Dean et al.
patent: 4349352 (1982-09-01), Manning
patent: 4399227 (1983-08-01), Niederau
patent: 4629692 (1986-12-01), Dean
patent: 4642295 (1987-02-01), Baker
patent: 4645742 (1987-02-01), Baker
patent: 4820636 (1989-04-01), Hill et al.
patent: 4861728 (1989-08-01), Wagner
patent: 4876188 (1989-10-01), Smith et al.
Scouten et al., Solid Phase Biochemistry, Wiley, New York, Chapter 4, pp. 149-187, (1983).
Kricka Larry J.
Wilding Peter
Hill Jr. Robert J.
The Trustees of the University of Pennsylvania
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