Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-01-25
2005-01-25
Housel, James (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007920, C436S064000
Reexamination Certificate
active
06846642
ABSTRACT:
The present invention is directed to diagnostic methods based upon the expression of the protein prostasin. In particular, it is concerned with assays performed on women to determine their risk of ovarian cancer.
REFERENCES:
patent: 5604106 (1997-02-01), Liotta et al.
patent: 5695761 (1997-12-01), Denhardt et al.
patent: 5712104 (1998-01-01), Yamamoto
patent: 5801004 (1998-09-01), Hudson et al.
patent: 5866119 (1999-02-01), Bandman et al.
patent: 5928883 (1999-07-01), Gleich et al.
patent: 6414219 (2002-07-01), Denhardt et al.
patent: 6686444 (2004-02-01), Ashkar
patent: 20020039753 (2002-04-01), Chai et al.
patent: 20020052308 (2002-05-01), Rosen et al.
Coolen et al., “Evaluation of Brain-Type Creatine Kinase in Serum From Patients With Carcinoma,” Cancer, vol. 44, pp. 1414-1418 (1979).*
Chen et al., “Prostasin Serine Protease Inhibits Breast Cancer Invasivness and is Transcriptionally REgulated by Promoter DNA Methylation,” Int. J. Cancer, vol. 97, pp. 323-329 (2002).*
Derisi, et al., “Use of a cDNA Microarray to Analyse Gene Expression Patterns in Human Cancer,”Nature Genetics 14:457-460 (1996).
Heid, et al., “Real Time Quantitative PCR,”Genome Research 6:986-994 (1996).
Kurtz, et al., “Serum Creatine Kinase BB Isoenzyme as a Diagnostic Aid in Occult Small Cell Lung Cancer,”Cancer 56:562-566 (1985).
Mok, et al., “Molecular Cloning of Differentially Expressed Genes in Human Epithelial Ovarian Cancer,”Gynecologic Oncology 52:247-252 (1994).
Mok, et al., “SPARC, an Extracellular Matrix Protein with Tumor-Suppressing Activity in Human Ovarian Epithelial Cells,”Oncogene 12:1895-1901 (1996).
Müeller-Pillasch, et al., “Cloning of a Gene Highly Overexpressed in Cancer Coding for a Novel KH-Domain Containing Protein,”Oncogene 14:2729-2733 (1997).
Schriml, et al., “Tyramide Signal Amplification (TSA)-FISH Applied to Mapping PCR-Labeled Probes Less than 1 kb in Size,”Biotechniques 27:608-613 (1999).
Schummer, et al., “Comparative Hybridization of an Array of 21 500 Ovarian cDNAs for the Discovery of Genes Overexpressed in Ovarian Carcinomas,”Gene 238:275-385 (1999).
Sharp, et al., “Tumor Cells are the Source of Osteopontin and Bone Sialoprotein Expression in Human Breast Cancer,”Laboratory Investigation 79:869-877 (1999).
Szala, et al., “Molecular Cloning of cDNA for the Carcinoma-Associated Antigen GA733-2,”Proc. Natl. Acad. Sci. 87:3542-3546 (1990).
Tuck, et al., “Osteopontin Induces Increased Invasiveness and Plasminogen Activator Expression of Human Mammary Epithelial Cells,”Oncogene 18:4237-4246 (1999).
Wang, et al., “Monitoring Gene Expression Profile Changes in Ovarian Carcinomas Using cDNA Microarray,”Gene 229:101-108 (1999).
Yu, et al., “Molecular Cloning, Tissue-Specific Expression, and Cellular Localization of Human Prostasin in mRNA,”Journal of Biological Chemistry 270:13483-13489 (1995).
Yu, et al., “Prostasin Is a Novel Human Serine Proteinase from Seminal Fluid,”Journal of Biological Chemistry 269:18843-18848 (1994).
Berteau, et al., “Prostasin mRNA to Detect Prostate Cells in Blood of Cancer Patients,”Clin. Chem. Lab. Med. 37:S119 (1999).
Chen, et al., “Down-Regulation of Prostasin Serine Protease: A Potential Invasion Suppressor in Prostate Cancer,”Prostate 48:93-103 (2001).
Hooper, et al., “Testisin, a New Human Serine Proteinase Expressed by Premeiotic Testicular Germ Cells and Lost in Testicular Germ Cell Tumors,”Cancer Res. 59:3199-3205 (1999).
Hooper, et al., “Localization, Expression and Genomic Structure of the Gene Encoding the Human Serine Protease Testisin,”Biochimica et Biophysica Acta 1492:63-71 (2000).
Yiu, et al., “Prostasin, a Potential Serum Marker for the Early Detection of Ovarian Cancer”Proceedings of the American Association for Cancer Research Annual 42:744 (2001).
Ali, et al., “Intercellular Cell Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1, and Regulated on Activation Normal T Cell Expressed and Secreted Are Expressed by Human Breast Carcinoma Cells and Support Eosinophil and Activation,”Am. J. Path. 157:313-321 (2000).
Alper, “Turning Sweet on Cancer,”Science 301:159-160 (2003).
Barker, et al., “Eosinophil Cationic Protein cDNA, Comparison with Other Toxic Cationic Proteins and Ribonucleases,”J. Immunol. 143:952-955 (1989).
Bast, et al., “A Radioimmunoassay Using a Monoclonal Antibody to Monitor the Course of Epithelial Ovarian Cancer,”N. Engl. J. Med. 309:883-887 (1983).
Beintema, et al., “Amino Acid Sequence of the Nonsecretory Ribonuclease of Human Urine,”Biochemistry 27:4530-4538 (1988).
Blumenthal, et al., “Degranulating Eosinophils in Human Endometriosis,”Am. J. Path. 156:1581-1588 (2000).
Cheung, et al., “Identify Metastasis-Associated Genes in Hepatocellular Carcinoma through Clonality Delineation for Multinodular Tumor,”Cancer Res. 62:4711-4721 (2002).
Cramer, et al., “Carotenoids, Antioxidants and Ovarian Cancer Risk in Pre- and Postmenopausal Women,”Int. J. Cancer 94:128-134 (2001).
Daly, et al., “The Search for Predictive Patterns in Ovarian Cancer: Proteomics Meets Bioinformatics,”Cancer Cell 1:111-112 (2002).
Denhardt, et al., “Osteopontin: A Protein with Diverse Functions,”FASEB J. 7:1475-1482 (1993).
Dorta, et al., “Tumor-Associated Tissue Eosinophilia as a Prognostic Factor in Oral Squamous Cell Carcinomas,”Histopathology 41:152-157 (2002).
Fernández-Aceñero, et al., “Prognostic Influence of Tumor-Associated Eosinophilic Infiltrate in Colorectal Carcinoma,”Cancer 88:1544-1548 (2000).
Fish, et al., “Changes in Serum Acute Phase Proteins in Ovarian Cancer Patients Receiving Cis-Diamminedichloro-platinum (CDDP) Infusion Therapy,”Clinical Biochem. 17:39-41 (1984).
Fish, et al., “Serum Haptoglobin and α1-Acid Glycoprotein as Indicators of the Effectiveness of cis-Diamminedichloroplatinum (CDDP) in Ovarian Cancer Patients—a Preliminary Report,”Eur. J. Cancer Clin. Oncol. 20:625-630 (1984).
Giachelli, et al., “Molecular and Cellular Biology of Osteopontin,”Trends Cardiovasc. Med. 5:88-95 (1995).
Gingrich, et al., “Metastatic Prostate Cancer in a Transgenic Mouse,”Cancer Res. 56:4096-4102 (1996).
Hakomori, “Glycosylation Defining Cancer Malignancy: New Wine in an Old Bottle,”Proc. Natl. Acad. Sci. USA 99:10231-10233 (2002).
Hamann, et al., “Sequence of Human Eosinophil-Derived Neurotoxin cDNA: Identity of Deduced Amino Acid Sequence with Human Nonsecretory Ribonucleases,”Gene 83:161-167 (1999).
Hamann, et al., “Structure and Chromosome Localization of the Human Eosinophil-Derived Neurotoxin and Eosinophil Cationic Protein Genes: Evidence for Intronless Coding Sequences in the Ribonuclease Gene Superfamily,”Genomics 7:535-546 (1990).
Hawley, et al., “Cancer Cells Release a Covalent Complex Containing Disulfide-Linked Domains from Urinary Plasminogen Activator, Neural Cell Adhesion Molecule, and Haptoglobin α and β Chains,”Arch. Biochem. Biophys. 345:289-298 (1997).
Kakugawa, et al., “Up-Regulation of Plasma Membrane-Associated Ganglioside Sialidase (Neu3) in Human Colon Cancer and Its Involvement in Apoptosis Suppression,”Proc. Natl. Acad. Sci. USA 99:10718-10723 (2002).
Kibel, et al., “Loss of Heterozygosity at 12P12-13 in Primary and Metastatic Prostate Adenocarcinoma,”J. Urol. 164:192-196 (2000).
Kiefer, et al., “The cDNA and Derived Amino Acid Sequence for Human Osteopontin,”Nuc. Ac. Res. 17:3306 (1989).
Kim, et al., “Osteopontin as a Potential Diagnostic Biomarker for Ovarian Cancer,”JAMA 287:1671-1679 (2002).
Ko, et al., “Haptoglobin Typing and Quantitatio
Mok Samuel C.
Wong Kwong-Kwok
Battelle (Memorial Institute)
Fitch Even Tabin & Flannery
Housel James
Lucas Zachariah
Sanzo Michael A.
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