Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2003-12-09
2008-09-16
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200
Reexamination Certificate
active
07425413
ABSTRACT:
Subject matter includes design, synthesis, and propagation of synthetic and semi-synthetic reference nucleic acids and mixtures of reference nucleic acids for use in genetic tests, such as molecular screening, mutation testing, carrier testing, and diagnostic assays. In one implementation, methods are described for design, synthesis, and propagation of reference nucleic acid mixtures and a system is presented for using the mixtures.
REFERENCES:
patent: 5759822 (1998-06-01), Chenchik et al.
patent: 6110668 (2000-08-01), Strizhov et al.
patent: 6607911 (2003-08-01), Gordon et al.
patent: WO03/078570 (2003-09-01), None
Legay et al., Construction of an internal standard used in RT nested PCR for Borna Disease Virus RNA detection in biological samples. Vet. Res. (2000) 31: 565-572.
Christensen, Todd M. et al., “Design, Development, Validation, and Use of Synthetic Nucleic Acid Controls for Diagnostic Purposes and Application to Cystic Fibrosis Testing”, vol. 9, No. 3, Jul. 2007, pp. 315-319.
Loitsch, Stefan M. et al., “Reverse Transcription-Competitive Multiplex PCT Improves Quantification of mRNA in Clinical Samples-Application to the Low Abundance CFTR mRNA”, vol. 45, No. 5, May 1999, pp. 619-624.
European Search Report for Application No. 04813464.7, mailed Feb. 5, 2008 (7 pages).
PCT Notification of Transmittal of the International Search Report, Jun. 7, 2006.
PCT Written Opinion Of the International Searching Authority, Jun. 7, 2006.
Bejjani Bassem A.
Christensen Todd M.
Horlick Kenneth R.
Lee & Hayes PLLC
Sacred Heart Medical Center
Thomas David C
LandOfFree
Methods of designing, synthesizing, and propagating... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of designing, synthesizing, and propagating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of designing, synthesizing, and propagating... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3989758