Methods of delivering materials into the skin, and compositions

Details Methods of delivering materials into the skin, and compositions Methods of delivering materials into the skin, and compositions

1995-06-13

2000-08-01

Gardner-Lane, Sally

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 69, 424484, 424489, 514847, 514951, A61K 700, A61K 748

Patent

active

060963247

ABSTRACT:
The invention relates to a system for delivering materials into the skin of a subject, comprising applying to the skin a composition comprising such materials in combination with an effective amount of a carrier and/or micro-carrier. The invention further provides a method for implementing the absorption of materials applied to the skin, when such materials are combined with an effective amount of a carrier and/or micro-carrier. Also provided are compositions used therein.

REFERENCES:
patent: 5137875 (1992-08-01), Tsunewaga
patent: 5279824 (1994-01-01), Sawyer
patent: 5442053 (1995-08-01), della Valle
R. Kasai, et al., "High performance liquid chromatography of glycosides on a new type of hydroxyapatite column," J. Chromatography, 407, 205-210 (1987).
S. Tsuru, et al., "Adsorption and preparation of human viruses using hydroxyapatite column," Journal of Bio-medical Materials and Engineering, vol. 1 (1991).
R.G. Smith & S.A. Lee, "Large-scale isolation and partial purification of type C RNA viruses on hydroxyapatite," Analytical Biochemistry, 86, 252-263 (1978).
T. Kawasaki et al., "Hydroxyapatite high performance liquid chromatography: column performance of proteins" European Journal Biochem., 152, 361-371 (1985).
T. Kadoya et al., "A new spherical hydroxyapatite for high performance liquid chromatography of proteins," J. Liquid Chromatography, 9, 3543-3557 (1986).
D. Josic et al., "Purification of monoclonal antibodies by hydroxyapatite HPLC and size exclusion HPLC," Biol. Chem. Hoppe-Seyler, 372, 149-156 (1991).
M.J. Gorbunoff & S.N. Timasheff "The interaction of proteins with hydroxyapatite," Analytical Biochemistry, 136, 440-445 (1984).
American International Chemical's product information/sales brochure: "Pentax Ceramic Hydroxyapatite" (No date found).
T. Kadoya et al., "High performance liquid chromatography of proteins on a hydroxyapatite column," J. Liquid Chromatography, 11, 2951-2967 (1988).
S. Tsuru et al., "A rapid method for the isolation of functional human T lymphocytes using hydroxyapatite column fractionation," J. Immunological Methods, 106, 169-174 (1988).
Laboratory Skin Care, Inc. (LSC), Product Data Sheet (No date available).
T. Ogawa et al., Asahi optical Co. Ltd. Poster presentation at LCL, Stockholm, Jun. 25-30, 1989 (Text and Figures), "Normal Phase High Performance Liquid Chromatography of Glycosides on a New Ceramic Hydroxyapatite Beads Column".
Poster presentation at the 7th International Congress of Immunology, Berlin, Jul. 29-Aug. 5, 1989, (Text and Figures), "Pentax Cell Column for Isolation of Human T-Lymphocytes".
Macro-PrePR Ceramic Hydroxyapatite, BIO-RAD Data Sheet C-100 (No date available).

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