Methods of decreasing the hydrophobicity of fibroblast and other

Details Methods of decreasing the hydrophobicity of fibroblast and other Methods of decreasing the hydrophobicity of fibroblast and other

1981-04-17

1983-11-08

Bleutge, John C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 424 85, C07G 700

Patent

active

044141475

ABSTRACT:
A method for improving the stability and usefulness of interferon, including human fibroblast interferon, is disclosed. In this method, interferon is bonded to a non-hydrophobic substance to create a molecular complex that is less hydrophobic than untreated interferon.

REFERENCES:
patent: 4061538 (1977-12-01), Dorner
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Mizrahi et al., J. Biol. Chem., vol. 253, No. 21, pp. 7612-7615, 1978.
Inglot et al., Arch Immunol Ther. Exp., vol. 28 (2) p. 313-322, 1980-Abst.
Inglot et al., Arch. Virol., vol. 60 (1), pp. 43-50, 1979-Abst.
Bose et al., J. Biol. Chem., vol. 251, No. 6, pp. 1659-1662, 1976.
Bose et al., J. Biol. Chem., vol. 252, No. 23, pp. 8336-8337, 1977.
Vilcek et al., J. Clin. Micro., vol. 11, No. 1, pp. 102-105, Jan. 1980.

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