Methods of controlling proliferation and differentiation of...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

Reexamination Certificate

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C435S366000, C435S372000, C435S375000, C435S377000, C435S385000, C435S384000

Reexamination Certificate

active

06887704

ABSTRACT:
A cell population cultured ex-vivo in a culture medium under conditions permitting cells of the cell population to proliferate and, at the same time, reducing a capacity of the cells in utilizing cooper, the cells are hence expanded yet not further differentiated as compared to ex-vivo seeded cells from which the cell population developed.

REFERENCES:
patent: WO 9731647 (1997-09-01), None
patent: WO 9733978 (1997-09-01), None
patent: WO 9825634 (1998-06-01), None
patent: WO 9940783 (1999-08-01), None
Percival . Am .J. Clin. Nutr. 1998, vol. 67 p. 1064-1068.*
Cicuttini et al. Blood, 1992, vol. 80 , pp. 102-112.*
Piacibello et al, “Extensive Amplification and Self-Renewal of Human Primitive Hematopoietic Stem Cells from Cord Blood”, Blood, 89(8):2644-2653, 1997.
Freshney, R.Ian, “Culture of Animal Cells, A Manual of Basic Technique” 3rdEd., John Wiley & Sons, pp309-311, 327-328.
Observations on the Anemia and Neutropenia of Human Copper Deficiency, Zidar et al., American Journal of Hematology, 3: 1977, pp. 177-185.
Copper Deficiency with Pancytopenia During Total Parenteral Nutrition, Wasa et al., Journal of Parenteral and Enternal Nutrition, vol. 18, No. 3, 1994, pp 190-192.
Neutropenia Caused by Copper Deficiency: Possible Mechanism of Action, Percival, Nutrition Reviews, vol. 53, No. 3, Mar. 1995, pp 59-66.
Copper Uptake and Intracellular Distribution During Retinoic Acid-Induced Differentiation of HL-60 Cells, Bae et al., J. Nutr. Biochem., Sep. 1994, vol. 5, pp 457-461.
Retinoic Acid-Induced HL-60 Cell Differentiation is Augmented by Copper Supplementation1-4, Bae et al., American Institute of Nutrition, Jan. 1993, pp 997-1002.
HL-60 Cells Can Be Made Copper Deficient by Incubating with Tetraethylenepentamine1,2,3, Percival et al., American Institute of Nutrition, Aug. 25, 1992, pp 2424-2429.
Copper Deficiency and Sideroblastic Anemia Associated with Zinc Ingestion, Simon et al., American Journal of Hematology, 28, 1988, pp 181-183.
Anemia and Neutropenia in a Case of Copper Deficiency: Role of Copper in Noraml Hematopoiesis, Hirase et al., Acta Haematol, 1992, 87 pp 195-197.
Exposure of Primary Rat Hepatocytes in Long Term DMSO Culture to Selected Transition Metals Induces Hepatocyte Proliferation and Formation of Duct-Like Structure, Cable et al., Hepatology, vol. 26, No. 6, 1997, pp 1444-1457.
Extensive Amplification and Self-Renewal of Human Primitive Hematopoietic Stem Cells from Cord Blood, Piacibelio et al., Blood, vol. 89, No. 8, Apr. 16, 1997, pp. 2644-2653.
Culture of Animal Cells, Freshney, John Wiley & Sons, Third Edition, pp 309-311 and 327-328.
Metallothionein Expression and Concentrations of Cooper and Zinc are Associated with Tumor Differentiation in Hepatocellular Carcinoma, Tashiro-Itoh et al., Liver, 1997, 17, pp 300-306.
Murray, et al.,Clin. Exp. Immunol., 53:744-749 (1983).
Morimoto, et al.,Biochem. Int., 28(2):313-321 (1992).
Perrotti, et al.,Mol. Cell. Biol., 15(11):6075-6087 (1995).
Borthwick, et al.,J. Lab. Clin. Med., 95(4):575-580 (1980).
Kohroki, et al.,Leukemia Res., 22(5):405-412 (1998).
Lassila, et al.,Cell. Immunol., 122(2):319-328 (1989).
Lau, et al.,J. Biol. Chem., 249(18):5878-5884 (1974).
Peled, et al.,Blood, Abstract only, 92(10 Suppl. 1 part 1-2):618A-619A (1998).
Supplementar European Search Report for EP 99 93 8494, mailing date: Jan. 8, 2004.

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