Methods of combating pneumocystis carinii pneumonia and compound

Details Methods of combating pneumocystis carinii pneumonia and compound Methods of combating pneumocystis carinii pneumonia and compound

1992-10-13

1995-06-27

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5483044, A61K 31415, C07D23508

Patent

active

054280516

ABSTRACT:
Disclosed is a method of combating Pneumocystis carinii Pneumonia in a subject in need of such treatment. The method comprises administering to the subject an effective Pneumocystis carinii-combating amount of a bis-benzimidazole compound such as bis[5-(2-imidazolyl)-2-benzimidazolyl]methane, 1,4-bis[5-2-imidazolyl)-2-benzimidazolyl]butane, or a pharmaceutically acceptable salt thereof. Pharmaceutical formulations for carrying out the method and novel compounds are also disclosed, along with methods of combating Giardia lamblia.

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