Methods of assessing HIV integrase inhibitor therapy

Details Methods of assessing HIV integrase inhibitor therapy Methods of assessing HIV integrase inhibitor therapy

2007-03-13

2007-03-13

Guzo, David (Department: 1636)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

C435S006120, C435S091100, C435S091200, C435S091210

Reexamination Certificate

active

11203768

ABSTRACT:
The present invention relates to methods and products for the evaluation of HIV treatment. The methods are based on evaluating molecular events at the HIV integrase resulting in altered therapeutic efficacy of the investigated compounds. The methods rely on providing an integrase gene and evaluating either through genotyping or phenotyping the integrase gene. The present invention relates to the fields of diagnostics, drug screening, pharmacogenetics and drug development.

REFERENCES:
patent: 5935982 (1999-08-01), Dykstra et al.
patent: 0 834 507 (1998-04-01), None
patent: WO 99/50250 (1999-10-01), None
patent: WO 99/50256 (1999-10-01), None
patent: WO 00/27825 (2000-05-01), None

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