Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Patent
1997-07-08
1999-11-30
Beisner, William H.
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
204643, G01N 2726, G01N 27447
Patent
active
059936312
ABSTRACT:
Particles are subjected to travelling wave field migration (TWFM) to migrate the particles over an array of microelectrodes. Altered particles are produced by treating original particles in such a way so as to alter their TWFM characteristics and the altered TWFM characteristics are employed for analysis and/or separation of the altered particles. The particles may be cells, bacteria, viruses, biomolecules or plastics microspheres. They may be altered by binding to a ligand such as a metal microparticle via a selective linking moiety such as an antibody/antigen or oligonucleic acid, or be physical or chemical treatments.
REFERENCES:
patent: 4390403 (1983-06-01), Batchelder
patent: 4900414 (1990-02-01), Sibalis
patent: 5108568 (1992-04-01), Van Alstine
patent: 5228960 (1993-07-01), Liu et al.
patent: 5284558 (1994-02-01), Linhardt et al.
patent: 5431793 (1995-07-01), Wang et al.
patent: 5454472 (1995-10-01), Benecke et al.
Masuda S et al., "Movement of Blood Cells in Liquid by Nonuniform Traveling Field", IEEE Transactions on Industry Applications, Mar. 1988, pp. 217-222, vol. 24, No. 2, XP002025002.
Senichi Masuda et al, "Separation of Small Particles Suspended in Liquid by Nonuniform Traveling Field", IEEE Transactions on Industry Appln. vol. A-23 No. 3 May/Jun. 1987 pp. 474-480.
J.A.R. Price et al, "Applications of a new optical technique for measuring the dielectrophoretic behaviour if micro-organisms", Biochimica et Biophysica Acta vol. 964 (1988) pp. 221-230.
Rolf Hagedrn et al, "Traveling-wave dielectrophoresis of microparticles", Electrophoresis 1992 vol. 13 pp. 49-54.
W.D. Geoghegan et al, The Detection of Human B Lymphocytes by both Light and Electron Microscopy Utilizing Colloidal Gold Labeled Anti-Immunoglobulin;, Immunological Communications, vol. 7(1), pp. 1-12, (1978).
Y Huang et al, "Electrokinetic behaviour of colloidal particles in travelling electric fields: studies using yeast cells", J. Phys D: Appl. Phys 26(1993) pp. 1528-1535.
Masao Washizu, "Electrostatic manipulation of biological objects", Journal of Electrostatics 25 (1990) Jun., No. 1 pp. 109-123.
Huang Ying
MacGregor Alastair R.
Parton Adrian
Pethig Ronald
Pollard-Knight Denise V.
Beisner William H.
Scientific Generics Limited
Starsiak Jr. John S.
LandOfFree
Methods of analysis/separation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of analysis/separation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of analysis/separation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1667083