Methods of altering calcium transport

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S006120, C435S007100, C435S069100, C435S235100, C435S325000, C435S375000, C435S032000, C530S350000, C536S023100

Reexamination Certificate

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07078178

ABSTRACT:
Methods of altering transmembrane calcium transport by altering expression of a calcium-transport protein are described.

REFERENCES:
Colbert et al., “OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation inCaenorhabditis elegans,” The Journal of Neuroscience, 17(21):8259-8269 (1997).
Hoenderop et al., J. Biol. Chem., 274, pp. 8375-8378, 1999.
Lee et al. “EST210872 Normalized Rat Brain, Bento Soares Rattus sp. cDNA Clone RBRBS54 3' End, mRNA Sequence,” Database EMBL: Accession No. AI101583, Oct. 8, 1998, XP000960319 ISSN: 0021-9258.
Peng et al., “Molecular Cloning and Characterization of a Channel-like Transporter Mediating Intestinal Calcium Absorption,”J. Biol. Chem., 274(32):22739-22746, 1999.
Peng et al., “CaT1 Expression Correlates with Tumor Grade in Prostate Cancer”, Biochemical and Biophysical Research Communications, 282, pp. 729-734, 2001.
Romero et al., Methods Enzymol., 296, pp. 17-52, 1998.
Copy of Written Opinion from PCT/US00/17932, Jul. 10, 2001, 7 pages.

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