Methods of administering peptides that bind to the erythropoieti

Details Methods of administering peptides that bind to the erythropoieti Methods of administering peptides that bind to the erythropoieti

1995-06-07

1998-11-03

Walsh, Stephen

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 8, 514 12, 514 13, 514 14, 514 15, 435 691, A61K 3804, C07K 704, C12N 1500

Patent

active

058308512

ABSTRACT:
Peptides of 10 to 40 or more amino acid residues in length and having the sequence X.sub.3 X.sub.4 X.sub.5 GPX.sub.6 TWX.sub.7 X.sub.8 (SEQ ID NO:252) where each amino acid is indicated by standard one letter abbreviation; X.sub.3 is C; X.sub.4 is R, H, L, or W; X.sub.5 is M, F, or I; X.sub.6 is independently selected from any one of the 20 genetically coded L-amino acids; X.sub.7 is D, E, I, L, or V; and X.sub.8 is C, which bind and activate the erythropoietin receptor (EPO-R) or otherwise act as an EPO agonist, and methods for their use.

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