Methods of administering microencapsulated materials for...

Details Methods of administering microencapsulated materials for... Methods of administering microencapsulated materials for...

2006-09-12

2006-09-12

Saunders, David (Department: 1644)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S145100, C424S158100, C424S491000, C424S499000, C514S002600

Reexamination Certificate

active

07105158

ABSTRACT:
Compositions useful in treating immune modulated disease comprising an anticytokine antibody or immune active drug capable of modifying cytokine activity or modulating the immune system microencapsulated with a biodegradable nonantigenic material, such as albumin or PLGA. When the composition is introduced into a subject, it is phagocytosed by the target organ, the target organ digests the microsphere, releasing the drug or an active form or fragment thereof intracellularly. The drug then modifies the target organ function, thereby modulating it's activity. A method is disclosed for preparation of the microencapsulated composition.

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