Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Reexamination Certificate
2008-02-12
2010-02-02
Landsman, Robert (Department: 1647)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
C530S300000, C530S350000
Reexamination Certificate
active
07655463
ABSTRACT:
The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same.
REFERENCES:
patent: 4352883 (1982-10-01), Lim
patent: 4353888 (1982-10-01), Sefton
patent: 4407957 (1983-10-01), Lim
patent: 4883666 (1989-11-01), Sabel et al.
patent: 4968733 (1990-11-01), Muller et al.
patent: 4976859 (1990-12-01), Wechs
patent: 5084350 (1992-01-01), Chang et al.
patent: 5158881 (1992-10-01), Aebischer et al.
patent: 5284761 (1994-02-01), Aebischer et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5496804 (1996-03-01), Reed et al.
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 5618531 (1997-04-01), Cherksey
patent: 5641749 (1997-06-01), Yan et al.
patent: 5654007 (1997-08-01), Johnson et al.
patent: 5733729 (1998-03-01), Lipshutz et al.
patent: 5754524 (1998-05-01), Wark
patent: 5775320 (1998-07-01), Patton et al.
patent: 5780014 (1998-07-01), Eljamal et al.
patent: 5780019 (1998-07-01), Klier et al.
patent: 5785049 (1998-07-01), Smith et al.
patent: 5795716 (1998-08-01), Chee et al.
patent: 5798113 (1998-08-01), Dionne et al.
patent: 5800992 (1998-09-01), Fodor et al.
patent: 5814607 (1998-09-01), Patton
patent: 5834029 (1998-11-01), Bellamkonda et al.
patent: 5916555 (1999-06-01), Lee et al.
patent: 6284540 (2001-09-01), Milbrandt et al.
patent: 6299895 (2001-10-01), Hammang et al.
patent: 6361771 (2002-03-01), Tao et al.
patent: 6593133 (2003-07-01), Johansen et al.
patent: 6734284 (2004-05-01), Johansen et al.
patent: 7115257 (2006-10-01), Tao et al.
patent: 7276580 (2007-10-01), Sah et al.
patent: 7358228 (2008-04-01), Sah et al.
patent: 7442370 (2008-10-01), Sah et al.
patent: 2002/0002269 (2002-01-01), Milbrandt et al.
patent: 2002/0055467 (2002-05-01), Johansen et al.
patent: 2004/0077543 (2004-04-01), Sah et al.
patent: 2004/0230043 (2004-11-01), Johansen et al.
patent: 2004/0242472 (2004-12-01), Shelton et al.
patent: 2005/0158824 (2005-07-01), Pedersen et al.
patent: 2005/0181991 (2005-08-01), Shelton et al.
patent: 1 373 503 (2007-11-01), None
patent: 1 930 439 (2008-06-01), None
patent: WO 92/19195 (1992-11-01), None
patent: WO 93/06116 (1993-04-01), None
patent: WO 95/05452 (1995-02-01), None
patent: WO 97/08196 (1997-03-01), None
patent: WO 97/11964 (1997-04-01), None
patent: WO 98/32869 (1998-07-01), None
patent: WO 99/49039 (1999-09-01), None
patent: WO 00/01815 (2000-01-01), None
patent: WO 00/04050 (2000-01-01), None
patent: WO 00/18799 (2000-04-01), None
patent: WO 00/34475 (2000-06-01), None
patent: WO 00/73348 (2000-12-01), None
patent: WO 02/051433 (2002-07-01), None
patent: WO 02/060929 (2002-08-01), None
patent: WO 02/072826 (2002-09-01), None
patent: WO 02/078730 (2002-10-01), None
patent: WO 2004/094592 (2004-11-01), None
patent: WO 2004/108760 (2004-12-01), None
patent: WO 2007/042040 (2007-04-01), None
Airaksmen et al. (1999), GDNF family neurotrophic factor signaling: four masters, one servant,Mol Cell Neurosci, 13:313-325.
Atschul et al. (1997), “Gapped BLAST and PSI-BLAST: a new generation of protein database search programs,”Nucl. Acids Res., 25:3389-3402.
Baloh et al. (1998), “Artemm, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRα3-RET receptor complex,”Neuron, 21:1291-1302.
Borodovsky et al. (1995), “Detection of new genes in a bacterial genome using Markov models for three gene classes,”Nucl. Acids Res., 23:3554-3562.
Daopin et al. (1993), “Chrystal structure of TGF-β2 refined at 1.8 A resolution,”Proteins, 17:176-192.
Eigenbrot and Gerber (1997), “X-ray structure of glial cell-derived neurotrophic factor at 1 9 A resolution and implications for receptor binding,”Nat. Struct. Biol., 4:435-438.
Finsen et al. (1992), “Somatostatin and neuropeptide Y in organotypic slice cultures of the rat hippocampus: an immunocytochemical and in situ hybridization study,”Neurosci, 47:105-113.
GenBank Accession AA844072 (Dec. 31, 1998).
Gardell et al. (2003) “Multiple actions of systemic artemin in experimental neuropathy” Nat Med. 2003 9(11):1383-89.
Kim S.H. et al., Pain 50:355-363 (1992).
Lapchak (1977), “Therapeutic potential for glial cell line-derived neurotropic factor (GDNF) based upon pharmacological activities in the CNS,”Rev. Neurosci., 7:165-176).
Lapchak et al. (1996), “Pharmacological characterization of glial cell line-derived neurotrophic factor (GDNF): implications for GDNF as a therapeutic molecule for treating neurodegenerative diseases,”Cell Tissue Res., 286:179-189.
Lin et al. (1993), GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons,Science, 260:1130-1132.
Lorenz et al. (1996), “Heteromultimeric CLC chloride channels with novel properties,”Proc. Natl. Acad. Sci USA, 93: 13362-13366.
Massague et al. (1994), “The TGF-β family and its composite receptor,”Trends Cell Biol., 4:172-178.
Masure et al. (1999), “Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells,”Eur. J. Biochem, 266:892-902.
McDonald and Hendrickson (1993), “A structural superfamily of growth factors containing a cystine knot motif.,”Cell, 73:421-424.
Milbrandt et al. (1998), Persephin, a novel neurotrophic factor related to GDNF and neurturin,Neuron, 20:245-253.
Orozco et al., Society for Neuroscience Abstracts 26 (1-2): Abstract No. 412.7, (2000).
Robertson and Manson (1997), “The GDNF-RET signaling in partnership,”Trends Genet., 13:1-3.
Saarma and Sariola (1999),Microscopy Res.&Technique, 45:292-302.
Sah et al. Society for Neuroscience Abstracts 27(1):361 (2001).
Sanicola et al. (1997), “Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins,”Proc Natl Acad Sci USA, 94:6238-6243.
Sauer and Oertel (1994), “Progressive degeneration of nigrostriatal dopamine neurons following intrastraiatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat,”Neuroscience, 59:401-415.
Slooth and Gramsbergen (1995), “Detection of salicylate and its hydroxylated adducts 2.3- and 2.5-dihydroxybenzoic acids as possible indices for in vivo hydroxyl radical formation in combination with catechol- and indoleamines and their metabolites in cerebrospinal fluid and brain tissue,”J. Neurosci. Meth., 60:141-149.
Stoppini et al. (1991), “A simple method for organotypic cultures of nervous tissue,”J. Neurosci. Methods, 37:173-182.
Thompson et al. (1997), “The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools,”Nucl. Acids Res., 25:4876-4882.
Unsicker (1996), “GDNF: a cytokine at the interface of TGF-betas and neurotrophins,”Cell Tissue Res., 286:175-178.
Von Schwedler et al. (1993), “Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells,”J. Virol., 67:4945-4955.
Wang L.X. et al., Advanced Drug Delivery Reviews 55:949-965 (2003).
Zufferey et al. (1997), “Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo,”Nat. Biotechnol., 15:871-875.
Algvere et al., “Transplantation of RPE in age-related macular degeneration: observations in disciform lesions and dry RPE atrophy”, Graefe's Arch. Clin. Exp. Ophthalmol. 235:149-158 (1997).
Anderson, Human gene therapy, Nature 392:25-30 (1998).
Burgess et al., “Possible Dissociation of the Heparin-binding and Mitogenic Activities . . . Residue”, J. of Cell Biology 111:2129-2138 (1990).
Callister et al., Soc. for Neuroscience Abstracts 27(1):36.11, (2001).
Carmillo et al., Glial Cell Line-Derived Neurotrophic Facto
Johansen Teit E.
Rossomando Anthony
Sah Dinah W. Y.
Biogen Idec MA Inc.
Fish & Richardson P.C.
Landsman Robert
NsGene A/S
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