Methods, kits and antibodies for detecting parathyroid hormone

Details Methods, kits and antibodies for detecting parathyroid hormone Methods, kits and antibodies for detecting parathyroid hormone

2003-07-10

2010-10-26

Cheu, Jacob (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007920, C435S007930, C435S007940, C435S007950, C435S040500, C435S960000

Reexamination Certificate

active

07820393

ABSTRACT:
The present invention relates to novel methods and compositions useful for detecting whole parathyroid hormone at a physiological level and parathyroid fragments in a mammalian sample. Such detections may be useful to different parathyroid diseases or disorders in a subject, such as hyperparathyroidism and related bone diseases, from normal or non-disease states. One detects whole or non-fragmented (1 to 84) parathyroid hormone in a biological sample and optionally one or more of a selection of non-whole parathyroid hormone peptide fragments that may or may not function as a parathyroid hormone antagonists. By either comparing values or using independently the value of either the one or more of a selection of non-whole parathyroid hormone peptide fragments, the whole parathyroid hormone, or the combination of these values one is able to differentiate parathyroid and bone related disease states, as well as differentiate such states from normal states.

REFERENCES:
patent: 4369138 (1983-01-01), Lindall
patent: 4423037 (1983-12-01), Rosenblatt et al.
patent: 4508828 (1985-04-01), Lindall et al.
patent: 4656250 (1987-04-01), Morita et al.
patent: 4751284 (1988-06-01), Forssmann
patent: 4782044 (1988-11-01), Forssmann
patent: 4824777 (1989-04-01), Chang et al.
patent: 4895932 (1990-01-01), Forssmann
patent: 5354900 (1994-10-01), Matsuo et al.
patent: 5545553 (1996-08-01), Gotschlich
patent: 5656455 (1997-08-01), Wood et al.
patent: 5744444 (1998-04-01), Forssmann
patent: 6030790 (2000-02-01), Adermann et al.
patent: 6524788 (2003-02-01), Cantor
patent: 6743590 (2004-06-01), Cantor
patent: 6838264 (2005-01-01), Zahradnik et al.
patent: 2002/0110871 (2002-08-01), Zahradnik et al.
patent: 2002/0160945 (2002-10-01), Cantor
patent: 2003/0138858 (2003-07-01), Cantor
patent: 2004/0185536 (2004-09-01), Cantor
patent: 2004/0219598 (2004-11-01), Cantor
patent: 2004/0229281 (2004-11-01), Cantor
patent: 2005/0095631 (2005-05-01), Cantor
patent: 33 47 548 (1985-07-01), None
patent: 44 34 551 (1996-04-01), None
patent: 10236631 (2003-07-01), None
patent: 0 783 522 (2001-12-01), None
patent: WO91/06564 (1991-05-01), None
patent: WO93/06845 (1993-04-01), None
patent: WO94/03201 (1994-02-01), None
patent: WO96/10041 (1996-04-01), None
patent: WO-00/42437 (2000-07-01), None
patent: WO-03/039572 (2003-05-01), None
patent: WO-2004/011607 (2004-02-01), None
patent: WO-2004/028444 (2004-04-01), None
patent: WO-2004/031727 (2004-04-01), None
patent: WO-2005/018413 (2005-03-01), None
Slatopolsky et al. (Kidney Intl. 2000 58: 753-761).
Gao et al. J. Bone Mineral Res 2001 16: 605.
Lepage et al. Clinical Chemistry 1998 vol. 44, pp. 805-809.
Rucinski et al. Calcif Tissue Int. 1995 vol. 56, pp. 83-87.
Declaration of Julia A. Miller in Support of Nichols Institute Diagnostics, Inc.'s Motion for Leave to File Amended Complaint, filed Jan. 26, 2004.
Nichols Institute Diagnostics, Inc.'s Notice of Lodgement of Corrected Copy of Proposed Second Amended Complaint, Exhibit A to Declaration of Julia A. Miller in Support of Nichols' Jan. 26, 2004 Motion for Leave to File Amended Complaint, filed Feb. 23, 2004.
Declaration of Julia A. Miller in Support of Nichols Institute Diagnostics, Inc.'s Motion for Summary Judgement that the '790 Patent Claims are Valid and Infringed, filed Feb. 28, 2005.
Declaration of Thomas L. Cantor with Exhibit A, executed on Apr. 7, 2005.
Complaint for 1. Direct Patent Infringment, 35 U.S.C. § 271(a); and 2. Inducing Patent Infringment, 35 U.S.C. § 271 (b); filed in the United States District Court, Central District of California, Southern Division; Case No. CV04-8871 GPS (MANx).
Declaration of M. Andrew Woodmansee in Support of Motion for Summary Judgment Pursuant to 35 U.S.C. § 102(b) by Defendants Scantibodies Clinical Laboratory, Inc. and Scantibodies Laboratory, Inc., filed Feb. 25, 2003.
Delclaration of Brigham A. Fordham in Support of Scantibodies' Motion for Judgement on the Pleadings for Lack of Standing and Failure to Join an Indispensable Party or, in the Alternative, to Join a Necessary Party Pursuant to FRCP 19, filed Jul. 16, 2003.
Declaration of Peter R. Munson in Support of Nichols Institute Diagnostics, Inc.'s Opposition to Scantibodies' Motion for Judgment on the Pleadings for Lack of Standing and Failure to Join an Indispensable Party or, in the Alternative, to Join a Necessary Party Pursuant to FRCP 19, filed Sep. 18, 2003.
Declaration of M. Andrew Woodmansee in Support of Scantibodies' Motion for Judgment on the Pleadings for Lack of Standing and Failure to Join an Indispensable Party or, in the Alternative, to Join a Necessary Party Pursuant to FRCP 19, filed Sep. 24, 2003.
Declaration of Julia A. Miller in Support of Nichols Institute Diagnostics, Inc.'s Motion to Permit Service of its Supplemental Amended Complaint Under F.R.C.P. 15(d), filed Nov. 24, 2003.
Declaration of Katherine L. Parker in Support of Scantibodies' Reply to Nichols' Opposition to Motion for Judgement on the Pleadings and for Attorneys' Fees, filed Feb. 23, 2004.
Supplemental Expert Report of Larry W. Evans Pursuant to Rule 26(A)(2)(B), Fed. R. Civ. P.
Supplemental Expert Report of L. J. Deftos, MD, JD, LLM.
Expert Report of Joseph O. Falkinham, III, Ph.D. Adopting Supplemental Expert Report of L. J. Deftos, MD, JD, LLM.
Rebuttal Expert Report of Joseph O. Falkinham, III, Ph.D.
Rubuttal Expert Report of Ellen S. Vitetta, Ph.D.
Declaration of M. Andrew Woodmansee in Support of Motion for Summary Judgment Pursuant to 35 U.S.C.§ 102(b) by Defendants Scantibodies Clinical Laboratory, Inc. and Scantibodies Laboratory, Inc., filed Feb. 25, 2003.
Declaration of Brigham A. Fordham in Support of Scantibodies' Motion for Judgment on the Pleadings for Lack of Standing and Failure to Join an Indispensable Party or, in the Alternative, to Join a Necessary Party Pursuant to FRCP 19, filed Jul. 16, 2003.
Declaration of Peter R. Munson in Support of Nichols Institute Diagnostics, Inc.'s Opposition to Scantibodies' Motion for Judgment on the Pleadings for Lack of Standing and Failure to Join an Indispensable Party or, in the Alternative, to Join a Necessary Party Pursuant to FRCP 19, filed Sep. 18, 2003.
Declaration of M. Andrew Woodmansee in Support of Scantibodies' Motion for Judgment on the Pleadings for Lack of Standing and Failure to Join an Indispensable Party or, in the Alternative, to Join a Necessary Party Pursuant to FRCP 19, filed Sep. 24, 2003.
Declaration of Julia A. Miller in Support of Nichols Institute Diagnostics, Inc.'s Motion to Permit Service of its Supplemental Amended Complaint Under F.R.C.P. 15(d), filed Nov. 24, 2003.
Declaration of Katherine L. Parker in Support of Scantibodies' Reply to Nichols' Opposition to Motion for Judgment on the Pleadings and for Attorneys' Fees, filed Feb. 23, 2004.
Supplemental Expert Report of Larry W. Evans Pursuant to Rule 26(A)(2)(B), Fed. R. Civ. P.
Supplemental Expert Report of L. J. Deftos, MD, JD, LLM.
Expert Report of Joseph O. Falkinham, III, Ph.D. Adopting Supplemental Expert Report of L. J. Deftos, MD, JD, LLM.
Rebuttal Expert Report of Joseph O. Falkinham, III, Ph.D.
Rubuttal Expert Report of Ellen S. Vitetta, Ph.D.
Order Granting Scantibodies' Ex Parte Application for Leave to File Documents Under Seal, filed May 4, 2005.
Nichols Institute Diagnostics, Inc.'s Notice of and Ex Parte Application for Order to File Its Confidential Consolidated Declaration of April Alex in Support of Nichols' Opposition to Scantibodies' In Limine Motion Nos. 2 and 5 Under Seal, filed May 5, 2005.
Declaration of April Alex in Support of Nichols' Ex Parte Application for Order Sealing Its Confidential Consolidated Declaration of April Alex in Support of Nichols' Opposition to Scantibodies' In Limine Motion Nos. 2 and 5 Under Seal, filed May 5, 2005.
Confidential Consolidated Declaration of April Alex in Support of Nichols Institute Diagnostics, Inc.'s Opposition to Scantibodies' In Limine Motion Nos. 2 and 5, filed May 5, 2005.
Scantibodies' Ex Parte Application For Leave to File Documents Under Seal With Oppositions to Nichols' Motions In Limine, Filed

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