Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2006-09-26
2006-09-26
Hui, San-Ming (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
Reexamination Certificate
active
07112610
ABSTRACT:
This invention relates to certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders.
REFERENCES:
patent: 2003/0195251 (2003-10-01), Barta et al.
patent: WO 98/40055 (1998-09-01), None
patent: WO 98/40055 (1998-09-01), None
patent: WO 00/59864 (2000-10-01), None
patent: WO 02/073208 (2002-09-01), None
patent: WO 02/073208 (2002-09-01), None
patent: WO 03/082807 (2003-10-01), None
patent: WO 03/082807 (2003-10-01), None
patent: WO 2004/016259 (2004-02-01), None
patent: WO 2004/054559 (2004-07-01), None
patent: WO 2005/018621 (2005-03-01), None
patent: WO 2005/018622 (2005-03-01), None
patent: WO 2005/018670 (2005-03-01), None
SIBI, M. P., et al., “A new methodology for the synthesis of Beta-amino acids”, J Chem Soc Perkin Trans 1, 2000, pp. 1461-1466.
Arvanitis et al., Enantioselective synthesis of 2-substitured 3-amniopropanoic acid (Beta-alanine) derivatives which are Beta-analogues of aromatic amino acids, J. Chem. Soc. Perkin Trans. 1, (1998), pp. 521-528.
Bull S.D. et al, “Asymmetric Synthesis of Beta-amino Acid Scaffolds”, J. Chem Soc., Perkin Trans. 1, (2001), pp. 2931-2938, vol. 22.
Davies, S.G. et al, “Asymmetric Synthesis of Beta-Phenylalanine, Alpha-Methyl-Beta-Phenylalanines and Derivatives”, J. Chem. Soc., Chem. Commun., (1993), pp. 1153-1155.
Davies, S. G., et al, “A Succinct Asymmetric Synthesis of (2S,3R)-2-Methyl-3-aminopentanoic Acid Hydrochloride”, Synlett, (1994), pp. 117-118.
Dixon, W., “Efficient Analysis of Experimental Observations”, Ann. Rev. Pharmacol. Toxicol., (1980), pp. 441-462, vol. 20.
Evans, D.A. et al, “A General Method for the Synthesis of Enantiomerically Pure Beta-Substituted, Beta-Amino Acids through Alpha-Substituted Succinic Acid Derivatives”, J. Org. Chem., (1999), pp. 6411-6417, vol. 64.
Gee, N. S. et al, “The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the Alpha2Beta Subunit of a Calcium Channel”, J. Biol. Chem., (1996), pp. 5768-5776, vol. 271(10).
Hargreaves, K. et al, “A New and Sensitive Method for Measuring Thermal Nociception in Cutaneous Hyperalgesia”, Pain, (1988), pp. 77-88, vol. 32.
Hawkins J. et al., Asymmetric Michael Reactions of 3,5-Dihydro-4H-dinaphth[2,1-c:1',2'-e]azepine with Methyl Crotonate , J.Org.Chem., (1986), pp. 2820-2822, vol. 51.
Hill, R. K. et al., “Asymmetric Induction in the Thermal Reactions of Allylic Alcohols with N, N-Dimethylacetamide Dimethyl Acetal and Triethyl Orthoacetate”, J. Org. Chem., (1972), pp. 3737-3740, vol. 37, No. 23.
Ho, G.J. et al, “Lithium-Initiated Imide Formation. A Simple Method for N-Acylation of 2-Oxazolidinones and Bornane-2, 1—Sultam”,J. Org. Chem., (1995), pp. 2271-2273, vol. 60.
Ishikawa et al, “Chiral Lewis Acid-Hydroxylamine Hybrid Reagent for Enantioselective Michael Addition Reaction Directed Towards Beta-Amino Acids Synthesis”, Synlett, (1998), pp. 1291-1293, vol. 11.
Juaristi, E., “Enantioselective Synthesis Of Beta-Amino Acids”, Tetrahedron: Asymmetry, (1996), pp. 2233-2246, vol. 7, No. 8.
Lazar, L. et al, “A Simple Synthesis of Beta-Alkyl-Substituted Beta-Amino Acids”, Synth. Commun., (1998), pp. 219-224, vol. 28(2).
Liang, J. et al, “Synthesis of Unit A of Cryptophycin via a [2,3]-Wittig Rearrangement”, J. Org. Chem., (1999), pp. 1459-1463, vol. 64.
Paine, J.B. et al, “Pyrrole Chemistry. The Cyanovinyl Aldehyde Protecting Groups”, J. Org. Chem., (1976), pp. 2826-2835, vol. 41, No. 17.
Randall L.O., et al, “A Method for Measurement of Analgesic Activity On Inflamed Tissue”, Arch. Int. Pharmacodyn., (1957), pp. 409-419, vol. 4.
Seebach, D. et al, “EPC—Synthesis of Beta-Amino Acid Derivatives through Lithiated Hydropyrimidines” Eur: J. Org. Chem., (1999), pp. 335-360.
Sluka, K., et al, “Unilateral Intramuscular Injections of Acidic Saline Produce a Bilateral Long-Lasting Hyperalgesia”, Muscle Nerve, (2001), pp. 37-46, vol. 24.
Tang, T. P. et al, “The tert-Butanesulfinyl Group: An Ideal Chiral Directing Group and Boc-Surrogate for the Asymmetric Synthesis and Applications of Beta-Amino Acids”, J. Org. Chem., (1999), pp. 12-13, vol. 64.
Vogel, J.R. et al, “A Simple and Reliable Conflict Proceure for Testing Anti-Anxiety Agents”, Psychopharmacologia, (1971), pp. 1-7, vol. 21.
Yuen P. W. et al, “Enantioselective Synthesis of PD144723: A Potent Stereospecific Anticonvulsant”, Bioorganic & Med. Chem Lett., (1994), pp. 823-825, vol. 4(6).
Bramson Candice
Haig George M.
Schrier Denis J.
Wang Fong
Ashbrook Charles W.
Hui San-Ming
Misiak Paul M.
Russo Matthew J.
Warner-Lambert Company LLC
LandOfFree
Methods for using amino acids with affinity for the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for using amino acids with affinity for the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for using amino acids with affinity for the... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3599129