Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1990-03-13
1991-10-15
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514450, 514861, 514863, 514864, A61K 31335, A61K 31715
Patent
active
050575015
ABSTRACT:
Certain compounds having sesquiterpene structures, when combined with monocarboxylic fatty acids, esters or amides, have efficacy in the treatment of papulosquamous and eczematous diseases. Prime examples of the sesquiterpene compounds are artemisinin and analogs, and prime examples of the monocarboxylic fatty acid compounds are lauric acid, monolaurin and lauryl-N,N-dimethylamide.
REFERENCES:
patent: 3535422 (1970-10-01), Cox et al.
patent: 4978676 (1990-12-01), Thornfeldt
Who, "The Development of Artemisinin And Its Derivatives: Report of a Meeting of the Scientific Working Group on the Chemotherapy of Malaria", Geneva, 6-7 Oct. 1986.
D. L. Klayman, "Qinghaosu (Artemisinin): An Antimalarial Drug from China", Science, vol. 228, 31 May 1985.
Krungkrai, S. R. et al., "The Antimalarial Action of Plasmodium Falciparum of Qinghaosu and Artesunate in Combination with Agents which Modulate Oxidant Stress", Transactions of The Royal Society of Tropical Medicine and Hygiene (1987), 81, 710-714.
Dermatologic Research Corporation
Schenkman Leonard
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