Methods for treating teeth with anticariogenic and antimicrobial

Drug – bio-affecting and body treating compositions – Dentifrices

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424 52, 424 53, 424673, 514900, 514944, 433215, A61K 716, A61C 500

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057701822

ABSTRACT:
The present invention discloses sustained release dental compositions, such as tooth bleaching or fluoride-containing compositions, having high viscosity and stickiness for treating tooth surfaces. For maximum results, an improved dental tray having reservoirs for holding the dental composition adjacent to the tooth surfaces being treated is preferably used in conjunction with the sustained release dental compositions. The sustained release dental compositions include carboxypolymethylene in a concentration in a range from about 3.5% to about 12% by weight of the dental composition, as well as a base so that the pH of the dental composition is in a range from about 5 to about 7, which results in a very high viscosity composition. The carboxypolymethylene also inhibits dilution of the dental compositions by saliva so that the compositions stay within the tray reservoirs over time, thereby providing sustained release, or prolonged delivery, of the active dental agent. The carboxypolymethylene adds a unique tackiness to the dental composition that helps to retain and seal the soft tray material against the patient's teeth.

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