Methods for treating resistant tumors

Details Methods for treating resistant tumors Methods for treating resistant tumors

1996-06-28

2000-09-26

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514 34, 5142325, 5142327, 514324, 514422, 514449, 514629, A61K 3144, A61K 3170, A61K 31535, A61K 31445, A61K 3140, A61K 31335, A61K 3116

Patent

active

061243116

ABSTRACT:
The present invention provides methods for reversing multidrug resistance in a resistant neoplasm by treating a mammal in need of said treatment with a substituted indole, benzofuran, benzothiophene, naphthalene, or dihydronaphthalene. This invention also provides methods for treating neoplasms in a mammal which comprises administering to a mammal in need of this treatment a substituted indole, benzofuran, benzothiophene, naphthalene, or dihydronaphthalene in combination with an oncolytic agent.

REFERENCES:
patent: 4133814 (1979-01-01), Jones et al.
patent: 4230862 (1980-10-01), Suarez et al.
patent: 4380635 (1983-04-01), Peters
patent: 5482949 (1996-01-01), Black et al.
Jones, et al., J. Med. Chem., 27:1057-1066 (1984).
M. Lehnert, J. Neuro-Oncology, 22:239-243 (1994).
Osborne, et al., J. Clinical Oncology, 7(6):710-717 (1989).
Carter et al., Chemotherapy of Cancer, 2nd Ed, (1981) pp. 82 and 83.

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