Methods for treating implantable biological tissues to...

Surgery – Blood vessel or graft preparation

Reexamination Certificate

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C623S002130, C623S915000, C008S094110, C514S693000

Reexamination Certificate

active

07029434

ABSTRACT:
A method for treating fixed biological tissue inhibits calcification of the biological tissue following implantation thereof in a mammalian body. The method includes placing the biological tissue in contact with glutaraldehyde and then heating the glutaraldehyde. Alternatively, methods other than heating (e.g., chemical or mechanical means), for effecting polymerization of the glutaraldehyde may also be utilized. Alternatively, the tissue may be heat treated prior to fixing thereof. Alternatively, methods other than glutaraldehyde may also be used for fixing the tissue. The biological tissue may be so treated at any time prior to implantation thereof in a mammalian body.

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