Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1999-02-23
2000-08-29
Schwartzman, Robert A.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C07K 100
Patent
active
061110779
ABSTRACT:
Method for screening for a non-hormone agent potentially useful to treat a hormone disorder The method involves contacting a potential agent with a system containing a cellular component and a translation factor. The component and factor interact with one another in an intact normal cell in a manner responsive to the hormone to cause a modulation of translation in the cell. The method involves determining whether the agent causes a modulation of translation by the component and the factor analogous to that which occurs in intact cells in response to the hormone.
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Harford Joe B.
Miles Vincent J.
Pause Arnim
Sonenberg Nahum
McGill University
Ousley Andrea
RiboGene, Inc.
Schwartzman Robert A.
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