Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2007-01-16
2007-01-16
Hui, San-Ming (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C514S171000, C514S180000, C514S181000
Reexamination Certificate
active
10257656
ABSTRACT:
This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for treating delirium. Mifepristone, a potent specific glucocorticoid receptor antagonist, can be used in these methods. The invention also provides a kit for treating delirium in a human including a glucocorticoid receptor antagonist and instructional material teaching the indications, dosage and schedule of administration of the glucocorticoid receptor antagonist.
REFERENCES:
patent: 6150349 (2000-11-01), Schatzberg et al.
patent: WO 99/17779 (1999-04-01), None
patent: WO 99/59596 (1999-11-01), None
patent: WO 02/076390 (2002-10-01), None
Abstract of Campbell et al., Gen Hosp Psychiatry, 1991;13(4):270-272.
Abstract of Fang et al., 1989;69(5):1073-1077.
Berkow, R., et al., “Brain and Nerve Disorders: Delirium and Dementia,”The Merck Manual of Medical Information(Home Edition), 1997, pp. 396-398.
Campbell, K., et al., “Delirium After Cessation of Clucocorticoid Therapy,”General Hospital Psychiatry, 1991, pp. 270-272, vol. 13, New York, U.S.A.
O'Keeffe, S.T., et al., “Delirium and the Dexamethasone Suppression Test in the Elderly,”Neuropsychobiology, 1994, pp. 153-156, vol. 30.
Corcept Therapeutics, Inc.
Hui San-Ming
Townsend and Townsend / and Crew LLP
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