Methods for treating arteriosclerosis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514399, 514824, A61K 31415

Patent

active

053589599

ABSTRACT:
The applicant has identified a particular class of imidazoles that inhibit endothelial cell, vascular smooth muscle cell and fibroblast proliferation. These imidazoles can be used to beneficially treat a variety of arteriosclerotic conditions.

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Forgue-Lafitte et al., Cancer Research 52, p. 6827-6831, Dec. 1992.
Teanakakis et al., Cancer 65, pp. 446-451, 1990.
Nardone et al., J. of Surg. Res. 44, pp. 425-429, 1988.

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