Methods for the treatment of ventricular dysrhythmia and prevent

Details Methods for the treatment of ventricular dysrhythmia and prevent Methods for the treatment of ventricular dysrhythmia and prevent

1983-09-26

1986-04-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, 514422, A61K 31445, A61K 3140

Patent

active

045843023

ABSTRACT:
Various indole and benzothiophene compounds having a pendant pyrrolidinylidene amino or piperidinylideneamino group are useful in the prevention of ventricular fibrillation, e.g., in humans. The invention comprises methods for the treatment of ventricular dysrhythymia or the prevention of ventricular fibrillation.

REFERENCES:
patent: 4059583 (1977-11-01), McComsey et al.
W. E. Hageman, Archives Internationals de Pharmacodynamie et de Therapie, vol. 237, No. 2 (1979).
Journal of Medicinal Chemistry, 1983, 28,230, M. J. Zelesko.

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