Methods for the treatment of arthritis using phosphonates and NS

Details Methods for the treatment of arthritis using phosphonates and NS Methods for the treatment of arthritis using phosphonates and NS

1995-06-07

1999-02-09

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

514570, A61K 31615, A61K 3119

Patent

active

058694714

ABSTRACT:
The present invention provides methods of treating a human or other animal subject afflicted with arthritis, including rheumatoid, arthritis and osteoarthritis, comprising a sixty (60)-day treatment period, comprised of an optional NSAID administration regimen and a phosphonate administration regimen, wherein

REFERENCES:
patent: 3676554 (1972-07-01), McGusty et al.
patent: 3887707 (1975-06-01), Sutton et al.
patent: 4216212 (1980-08-01), Flora et al.
patent: 4264582 (1981-04-01), Flora et al.
patent: 4269828 (1981-05-01), Flora et al.
patent: 4275059 (1981-06-01), Flora et al.
patent: 4282214 (1981-08-01), Flora et al.
patent: 4330530 (1982-05-01), Baker
patent: 4687768 (1987-08-01), Benedict et al.
patent: 4746654 (1988-05-01), Breliere et al.
patent: 4868164 (1989-09-01), Ebetino et al.
patent: 4876247 (1989-10-01), Barbier et al.
patent: 4939130 (1990-07-01), Jaeggi et al.
patent: 4939131 (1990-07-01), Benedict et al.
patent: 5071840 (1991-12-01), Ebetino et al.
patent: 5104863 (1992-04-01), Benedict et al.
patent: 5137880 (1992-08-01), Ebetino et al.
Forys, Victor A., "Etidronate and Osteoarthritis" (Letter to the Editor), Jama 265(21):2807 (Jun. 5, 1991).
McGuire, Mary K.B., "Biochemical Mechanisms in Arthritis", Sep. 1981, p. 265 (Thesis submitted to the University of Sheffield).
Ralston, Stuart H., "Clinical, biochemical, and radiographic effects of aminohydroxpropylidene bisphosphonate treatment in rheumatoid arthritis", Ann. Rheum. Diseases 48(5), pp. 396-399 (May 1989).
Heynen, G., et al., Diphosphonates and Rheumatoid Arthritis (RA), Abstracts. ILAR XVth International Congress of Rheumatology, Paris, France, Jun. 21-27, 1981, Rev. Rhum. Mal. Osteoartic., Special Number: 139 (Jun. 1981).
Lane, Nancy, et al., "Effect of Naproxen on Cancellous Bone in Ovariectomized Rats", Journal of Bone and Mineral Research, vol. 5, No. 10 (1990).
Kimmel, D.B., et al., "Long-Term Effect of Naproxen on Cancellous Bone in Ovariectomized Rats", Bone, 13, pp. 167-172 (1992).
Francis, M.D., et al., "The Effects of Disodium Ethane-1-Hydroxy-1,1-Diphosphonate on Adjuvant Induced Arthritis in Rats", Calcif. Tissue Res. 9, pp. 109-121 (1972).
Bird, H.A., et al., "A clinical and biochemical assessment of etidronate disodium in patients with active rheumatoid arthritis", Clin. Rheumatol. 7(1), pp. 91-94 (1988).
Flora, L., "Comparative Antiinflammatory and Bone Protective Effects of Two Diphosphonates in Adjuvant Arthritis", Arthritis and Rheumatism, vol. 22, No. 4, pp. 340-346 (Apr. 1979).
Couchman, K.G., et al., "The effect of anti-rheumatic drugs on factors from porcine synovium inducing chondrocyte mediated cartilage degradation", Agents and Actions, vol. 19 (1-2), pp. 116-122 (Oct. 1986).
Movsowitz, C., et al., "The bisphosphonate 2-PEBP inhibits cyclosporin A induced high-turnover osteopenia in the rat", J. Lab. Clin. Med. 115(1), pp. 62-68 (Jan. 1990).

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