Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1983-01-24
1985-12-03
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
424131, 424132, 424147, 514494, 514502, 514865, 15206, 604360, A61K 3324, A61K 3330
Patent
active
045565600
ABSTRACT:
Methods for the treatment and prevention of diaper rash and diaper dermatitis caused by the prolonged contact of human skin with body waste are disclosed. The methods of the present invention employ the topical application of a minimum inhibitory concentration of a pharmaceutically-acceptable lipase-inhibiting agent to the area in need of such treatment, or the area where prevention is desired. The lipase-inhibiting agent is preferably a water-soluble metallic salt, such as ZnCl.sub.2, and is preferably applied in combination with a barrier-like vehicle. The effectiveness of these methods is surprising in light of the present confusion and controversy surrounding the actual causes of diaper rash, and the heretofore unrecognized role of lipase as a factor in the cause of diaper rash and diaper dermatitis.
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Allen George W.
Goldstein Steven J.
Schaeffer Jack D.
Schenkman Leonard
The Procter & Gamble & Company
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