Methods for the solid phase synthesis of substituted indole comp

Details Methods for the solid phase synthesis of substituted indole comp Methods for the solid phase synthesis of substituted indole comp

1998-07-29

1999-08-03

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548490, 548491, 548504, 548506, 548507, 548509, 548510, 548511, C07D20908, C07D20910, C07D20912, C07D20914

Patent

active

059327430

ABSTRACT:
The present invention relates to novel substituted indole compounds of formula (I) ##STR1## having pharmacological activity, to processes for their preparation, to solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, and to pharmaceutical compositions thereof.

REFERENCES:
Hermkens, et al., Tetrahedron Lett., 52, 4527-4554 (1996).
Comprehensive Heterocyclic Chem., 4, 370-376; Pergamon Press, Oxford (1984).
Borman, S., Chemical & Engineering News, 75(8) 43-62 (1997).
Arcadi A., et al., Tetrahedron Lett., 33, 3915-3918 (1992).
Hutchins, S.M. et al., Tetrahedron Lett., 37, 4867-4872 (1996).
Fagnola et al., Tetrahedron Lett. 38 (13) 2307-2310 (1997).

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