Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2011-07-05
2011-07-05
Hama, Joanne (Department: 1632)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S320100
Reexamination Certificate
active
07972857
ABSTRACT:
The present invention includes compositions and methods for site-specific polynucleotide replacement in eukaryotic cells. These methods include single polynucleotide replacement as well as gene stacking methods. Preferred eukaryotic cells for use in the present invention are plant cells and mammalian cells.
REFERENCES:
patent: 5190871 (1993-03-01), Cox et al.
patent: 5527695 (1996-06-01), Hodges et al.
patent: 5744336 (1998-04-01), Hodges et al.
patent: 5910415 (1999-06-01), Hodges et al.
patent: 6110736 (2000-08-01), Hodges et al.
patent: 6114600 (2000-09-01), Ow et al.
patent: 6143530 (2000-11-01), Crouzet et al.
patent: 6175058 (2001-01-01), Baszczynski et al.
patent: 6187994 (2001-02-01), Baszczynski et al.
patent: 6262341 (2001-07-01), Baszczynski et al.
patent: 6632672 (2003-10-01), Calos
patent: 6746870 (2004-06-01), Ow et al.
patent: 6936747 (2005-08-01), Ow
patent: 2002/0123145 (2002-09-01), Ow et al.
patent: WO 97/37012 (1997-10-01), None
patent: WO 99/18222 (1999-04-01), None
patent: WO 99/25821 (1999-05-01), None
patent: WO 00/11155 (2000-03-01), None
patent: WO 00/60091 (2000-10-01), None
patent: WO 01/07572 (2001-02-01), None
Hasty et al., 1991, Molecular and Cellular Biology, 11: 5586-5591.
Albert, H. et al., “Site-specific integration of DNA into wild-type and mutant lox sites placed in the plant genome,”The Plant Journal(1995) 7(4):649-659.
Alonso, J.C. et al., “TheBacillus subtilisHistone-like Protein Hbus Is Required for DNA Resolution and DNA Inversion Mediated by the β Recombinase of Plasmid pSM19035,”The Journal of Biological Chemistry(1995) 270(7):2938-2945.
Araki, H. et al., “Site-specific Recombinase, R, Encoded by Yeast Plasmid pSR1,”J. Mol. Biol.(1992) 255:25-37.
Araki, K. et al., “Targeted integration of DNA using mutant lox sites in embryonic stem cells,”Nucleic Acids Research(1997) 25(4):868-872.
Argos, P. et al., “The integrase family of site-specific recombinases: regional similarities and global diversity,”The Embo Journal(1986) 5(2):433-440.
Bannam, T.L. et al., “Molecular genetics of the chloramphenicol-resistance transposon Tn4451 from Clostridium perfringens: the TnpX site-specific recombinase excises a circular transposon molecule,”Molecular Microbiology(1995) 16(3):535-551.
Baubonis, W. et al., “Genomic targeting with purified Cre recombinase,”Nucleic Acids Research(1993) 21(9):2025-2029.
Bayley, C.C. et al., “Exchange of gene activity in transgenic plants catalyzed by the Cre-lox site-specific recombination system,”Plant Molecular Biology(1992) 18:353-361.
Becker, D. et al., “Fertile transgenic wheat from microprojectile bombardment of scutellar tissue,”The Plant Journal(1994) 5(2):299-307.
Belteki, G. et al., “Site-specific cassette exchange and germline transmission with mouse ES cells expressing φC31 integrase,”Nature Biotechnology(2003) 21:321-324.
Bethke, B. et al., “Segmental genomic replacement by Cre-mediated recombination: genotoxic stress activation of the p53 promoter in single-copy transformants,”Nucleic Acids Research(1997) 25(14):2828-2834.
Bhattacharyya, M.K. et al., “Reduced variation in transgene expression from a binary vector with selectable markers at the right and left T-DNA borders,”The Plant Journal(1994) 6(6):957-968.
Carrasco, C.D. et al., “Anabaena xisF gene encodes a developmentally regulated site-specific recombinase,”Genes&Development(1994) 8:74-83.
Choi, S. et al., “A new approach for the identification and cloning of genes: the pBACwich system using Cre/lox site-specific recombination,”Nucleic Acids Research(2000) 28(7):e19 (i-vii).
Cluster et al., “Details of T-DNA structural organization from a transgenic Petunia population exhibiting co-suppression,”Plant Molecular Biology(1996) 32:1197-1203.
Corneille, S. et al., “Efficient elimination of selectable marker genes from the plastid genome by the CRE-lox site-specific recombination system,”The Plant Journal(2001) 27(2):171-178.
Crellin, P.K. et al., “The Resolvase/Invertase Domain of the Site-Specific Recombinase TnpX Is Functional and Recognizes a Target Sequence That Resembles the Junction of the Circular Form of the Clostridium perfringens Transposon Tn4451,”Journal of Bacteriology(1997) 179(16):5148-5156.
Crisona, N. J. et al., “Processive Recombination by Wild-type Gin and an Enhancer-independent Mutant,”J. Mol. Biol.(1994) 243:437-457.
Dale, E.C. et al., “Gene Transfer with subsequent removal of the selection gene from the host genome,”Proc. Nat. Acad. Sci.(1991) 88:10558-10562.
Dale, E.C. et al., “Infra- and intermolecular site-specific recombination in plant cells mediated by bacteriophage P1 recombinase,”Gene(1990) 91:79-85.
Davies, G.J. et al., “Somatic and germinal inheritance of an FLP-mediated deletion in transgenic tobacco,”Journal of Experimental Botany(1999) 50(338):1447-1456.
Day, C.D. et al., “Transgene integration into the same chromosome location can produce alleles that express at a predictable level, or alleles that are differentially silenced,”Gene&Development(2000) 14:2869-2880.
DeBuck, S., et al., “Transgene silencing of invertedly repeated transgenes is released upon deletion of one of the transgenes involved,”Plant Molecular Biology(2001) 46:433-445.
Diaz, V. et al., “The Prokaryotic β-Recombinase Catalyzes Site-Specific Recombination in Mammalian Cells,”The Journal of Biological Chemistry(1999) 274(10):6634-6640.
Diaz, V. et al., “New Insights into Host Factor Requirements for Prokaryotic β-Recombinase-mediated Reactions in Mammalian Cells,”The Journal of Biological Chemistry(2001) 276(19):16257-16264.
Feng, Y.-Q. et al., “Site-Specific Chromosonal Integration in Mammalian Cells: Highly Efficient CRE Recombinase-mediated Cassette Exchange,”J. Mol. Biol.(1999) 292:779-785.
Finkel, S.E. et al., “The Fis protein: it's not just for DNA inversion anymore,”Molecular Microbiology(1992) 6(22):3257-3265.
Forsburg, S.L., “Comparison of Schizosaccharomyces pombe expression systems,”Nucleic Acids Research(1993) 21(12):2955-2956.
Friedman, D.I., “Integration Host Factor: A Protein for all Reasons,”Cell(1988) 55:545-554.
Gilbertson et al., Conference on in Virto Technology St. Louis, In:In Vitro Cellular&Development Biology Animal(2001) 37 (3 part 2):26A.
Gleave, A.P. et al., “Selectable marker-free transgenic plants without sexual crossing: transient expression of cre recombinase and use of a conditional lethal dominant gene,”Plant Molecular Biology(1999) 40:223-235.
Golic, M.M. et al., “FLP-mediated DNA mobilization to specific target sites in Drosophila chromosomes,”Nucleic Acids Research(1997) 25(18):3665-3671.
Grimm et al., “Genetic engineering ofSchizosaccharomycespombe: A system for gene disruption and replacement using theura4gene as a selectable marker,”Mol. Gen. Genet.(1988) 215:81-86.
Groth, A.C. et al., “A phage integrase directs efficient site-specific integration in human cells,”PNAS(2000) 97(11):5995-6000.
Hajdukiewicz, P.T.J. et al., “Multiple pathways for Cre/lox-mediated recombination in plastids,”The Plant Journal(2001) 27(2):161-170.
Hatfull, G.F. et al., “Resolvases and DNA-Invertases: a Family of Enzymes Active in Site-Specific Recombination,” In:Genetic Recombination, Eds: R. Kucherlapati and G.R. Smith, (1988) Chapter 11 pp. 357-396.
Hohn, B. et al., “Elimination of selection markers from transgenic plants,”Current Opinion in Biotechnology(2001) 12:139-143.
Howe, M. et al., “Cis-Effects of Heterochromatin on Heterochromatic and Euchromatic Gene Activity in Drosophila melanogaster,”Genetics(1995) 140:1033-1045.
Hucl, P. et al., “Impact of marker genes on agronomic pe
Connor Margaret A.
Fado John D.
Hama Joanne
Sampson Elizabeth R.
The United States of America as represented by the Secretary of
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