Methods for the preparation of resins with ligands attached ther

Details Methods for the preparation of resins with ligands attached ther Methods for the preparation of resins with ligands attached ther

1996-01-11

1998-08-04

Nutter, Nathan M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536112, 536114, 536122, C08B 3702

Patent

active

057895783

ABSTRACT:
Disclosed are methods for the preparation of resins comprising a support matrix having ligands capable of binding a target compound covalently attached thereto through a linking group comprising sulfide, sulfoxide, or sulfone functionality. Specifically, in the disclosed methods, a support matrix comprising ethylenically unsaturated functionality is converted to sulfide linkage by contact with a thiol group under free radical reaction conditions and subsequent optional oxidation of the sulfide to the sulfone or sulfoxide functionality.

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