Methods for the manufacture of neofazodone

Details Methods for the manufacture of neofazodone Methods for the manufacture of neofazodone

1997-10-15

1999-05-04

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544393, C07D29513, C07D40306

Patent

active

059004851

ABSTRACT:
Process for the manufacture of triazolone compounds and in particular nefazodone and intermediates useful in the manufacture thereof.

REFERENCES:
patent: 3857845 (1974-12-01), Palazzo
patent: 4338317 (1982-07-01), Temple, Jr. et al.
patent: 5767275 (1998-06-01), Nigro et al.
Silvestrini et al, "Pharmacological Properties of AF 1161, A New Psychotropic Drug", Int. J. Neuropharmacol. 7:587-599 (1968).
Bertoletti, P., "Valutazione dell'efficacia e della tollerabilita di un nuovo psicofarmaco nella sindrome ansioso-depres-siva (confronto in doppio cieco versus diazepam)", G. Clin. Med. 58:393 (1977).

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