Methods for the manufacture of amorphous cefuroxime axetil

Details Methods for the manufacture of amorphous cefuroxime axetil Methods for the manufacture of amorphous cefuroxime axetil

1997-07-25

1998-12-08

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07B 6300, C07D50134

Patent

active

058471189

ABSTRACT:
A process for preparing pure amorphous cefuroxime axetil comprising the steps of dissolving crystalline cefuroxime axetil in a highly polar organic solvent and adding the resulting solution to water, or alternatively, dissolving crystalline cefuroxime axetil in a highly polar solvent and adding small quantities of water to the organic solution and adding the resulting organic-aqueous solution to water.

REFERENCES:
patent: 4820833 (1989-04-01), Crisp et al.
patent: 5013833 (1991-05-01), Crisp et al.
patent: 5677443 (1997-10-01), Zenoni

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