Methods for the isolation of bacteria containing eukaryotic gene

Details Methods for the isolation of bacteria containing eukaryotic gene Methods for the isolation of bacteria containing eukaryotic gene

1996-09-25

2000-02-08

Eisenschenk, Chris

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 34, 435 711, 4352402, 4352521, C12Q 104, C12N 516, C12N 508

Patent

active

060227303

ABSTRACT:
Bacteria containing eukaryotic and/or viral genes, and often having highly pleiomorphic morphology, are obtained by culturing virally-infected eukaryotic cells under aseptic, low oxygen conditions. The bacteria so produced express products encoded by the eukaryotic genes. Analyses indicate that several isolates obtained from culturing retrovirally-infected human brain capillary endothelial cells express human-specific genes previously mapped to widely separated human chromosomes.

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