Methods for the identification of cytokine convertase inhibitors

Details Methods for the identification of cytokine convertase inhibitors Methods for the identification of cytokine convertase inhibitors

1993-04-26

1995-06-06

Russel, Jeffrey E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

435 23, 435963, 530326, 530332, C07K 702, C07K 1481, C12Q 137

Patent

active

054224250

ABSTRACT:
Compositions and methods are described for identifying inhibitors of mature protein hormone formation from a prohormone, and prophylactic and therapeutic uses of the inhibitors for treating diseases associated with elevated levels of the mature hormones, particulary sepsis, and autoimmune diseases.

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