Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-12-12
2000-11-21
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549510, 560 39, 560170, C07C22900, C07D30500, C07D40700, C07D49300
Patent
active
061505374
ABSTRACT:
The invention relates to a method for preparing an ester, by admixing a compound having the structure I or IV: ##STR1## with a base and an alcohol to produce an ester, wherein the alcohol is a precursor to Taxol and its analogs. The present invention also relates to compounds having the structure I and IV and methods of making them therefor. The invention also relates to the esterification of an alcohol by adding an alkoxide to a compound having the structure VII: ##STR2## The invention further relates to compounds having the structure I, IV, and VII and methods of making them therefor. The invention further relates to alcohols, and in particular, alcohols that are synthetic precursors to Taxol and analogs thereof.
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Captain Laura
Liotta Dennis C.
Schestopol Marcus A.
Snyder James P.
Venkatesan Hariharan
Coleman Brenda
Emory University
Raymond Richard L.
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