Methods for the early diagnosis of ovarian cancer

Details Methods for the early diagnosis of ovarian cancer Methods for the early diagnosis of ovarian cancer

2011-05-03

2011-05-03

Falk, Anne-Marie (Department: 1632)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

Introduction of a polynucleotide molecule into or...

C424S093100

Reexamination Certificate

active

07935531

ABSTRACT:
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically, the present invention relates to expression of hepsin protease. The detected proteases are themselves specifically over-expressed in certain cancers, and the presence of their genetic precursors may serve for early detection of associated ovarian and other malignancies, and for the design of interactive therapies for cancer treatment.

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