Methods for the diagnosis of glaucoma

Details Methods for the diagnosis of glaucoma Methods for the diagnosis of glaucoma

1994-11-03

1997-02-25

Wax, Robert A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4353201, C07H 2104, C12N 1500

Patent

active

056060432

ABSTRACT:
A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.

REFERENCES:
patent: 5420120 (1995-05-01), Boltralik
patent: 5474985 (1995-12-01), Polansy et al.
Partridge et al. (1989) Invest. Opthamol. Visual Sci. 30(8):1843-1847.
Fauss et al. (1990) Invest. Opthamol. Visual Sci. 31(4):435.
Nguyen et al. `Cloning of glucocorticoid-induced proteins in HTM cells: verification of progressive, high dose dependent, cDNAs to correlate with effects on IOP`, Invest. Opthalmol. Vis Sci. 32:789 (1990).

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